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In the ongoing effort to find new therapeutics for infants born infected with the human immunodeficiency virus, an international team of investigators has discovered that babies can tolerate treatment with anti-HIV antibodies.

As the leading cause of viral gastroenteritis worldwide, norovirus is an all too familiar ailment. Its telltale digestive upset—not to mention its reputation for being notoriously contagious—has earned it the nicknames "winter vomiting bug" and "stomach flu." Yet despite millions

An international research team led by investigators in the Department of Microbiology at the Icahn School of Medicine at Mount Sinai has developed the first fully human monoclonal antibody cocktail shown to provide complete protection against lethal Nipah and Hendra virus infecti

Lyme disease can be easiest to treat in its earliest stages, but current tests often miss infections during that critical window and cannot tell whether bacteria are still present or were cleared years ago. New research led by Tufts University School of Medicine suggests that a g

A drug commonly used to treat epilepsy could be repurposed to significantly boost the response to vaccines in humans, helping protect those for whom the vaccine is less effective, such as older adults or immunocompromised people. A Cambridge-led team showed that the drug more tha

A new HIV vaccine developed by La Jolla Institute for Immunology (LJI), Scripps Research scientists and IAVI has the potential to protect humans from developing HIV infection and AIDS. This HIV vaccine is the first to generate a high number of "broadly neutralizing" virus-fightin

In people with severely compromised immune systems, JC polyomavirus can trigger an untreatable, often fatal brain disease. An international research team has identified how virus mutations can strategically interfere with how human antibodies recognize the virus, allowing it to e

A lot of things need to go right on a molecular level for immune cells to launch an adaptive response to an infection. B cells can produce different classes of antibodies tailored for specific infections through controlled DNA damage and repair that alter the genetic information

A delivery system that uses lipid nanoparticles to sneak proteins into cells can accomplish the same feat by smuggling therapeutic antibodies, new research has found.