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OpenAI has built an LLM super-hacker called GPT-Red that it uses as a sparring partner to help its other models boost their defenses against cyberattacks. Last week the company released the latest version of its flagship LLM, GPT-5.6. OpenAI says that training it against GPT-Red

Blocking IL1RAP, a receptor that sits at a key control point in inflammatory signaling, can disrupt the tumor-driven inflammatory network that helps pancreatic cancer resist treatment, according to new research. Led by researchers at Sylvester Comprehensive Cancer Center, part of

Cholesterol-related heart disease remains the leading cause of death worldwide, and while doctors have more tools than ever to treat it, many patients still can't achieve safe cholesterol levels or can't tolerate the side effects of available medications.

A new "tumor-on-a-chip" model is giving scientists a live look at how pancreatic cancer can recruit the body's own immune cells to help tumors survive. Researchers say the findings, published in Biofabrication, reveal possible new targets to weaken the cancer's defenses and make

Warmer temperatures bring out ticks that spread diseases such as Lyme disease and Rocky Mountain spotted fever. But another class of emerging tick-borne pathogens—nairoviruses—is on the rise. Some nairoviruses cause high fevers and reduce organ function in people exposed to certa

A new study sheds light on how the ancestors of modern land plants survived one of the most challenging aspects of life outside water: exposure to harmful ultraviolet (UV) radiation. By examining a microscopic alga closely related to the earliest land plants, researchers have unc

A new study of wild bats reveals that an animal's immune system is shaped by more than its need to fight infections. Researchers from the University of Maryland have found that sex, age and competition for mates influence how bats balance different types of immune defenses—provid

When a company faces the prospect of a hostile takeover, its board may reach for traditional anti-takeover defenses. "Poison pills," for instance, allow existing shareholders to buy additional shares at a discount, diluting a would-be acquirer's stake and making the target more e

As a heat dome drives dangerous temperatures across much of the United States and renews concerns about extreme heat, USC researchers have developed a new, freely available AI tool that could help cities better understand one of their best defenses against rising temperatures: tr

A deadly fungus has wiped out amphibian populations around the globe, yet some mysteriously recover. Researchers discovered that survivors develop powerful immune defenses while they are still tadpoles, giving them a head start before the fungus can attack after metamorphosis. Th