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The Ross Procedure, a highly specialized option for aortic valve replacement, is associated with significant long-term durability and excellent outcomes in a wide range of adult patients with aortic valve disease. These are the results of a new study led by Mount Sinai heart surg

Anti-angiogenic therapies targeting VEGF have been widely used in cancer treatment, yet their long-term efficacy remains limited. Tumor vascular endothelial cells (TECs) exhibit high adaptive plasticity, enabling them to resist treatment and sustain tumor growth, but the molecula

Results of the ongoing eNRGy trial, a single-arm, multicenter, global Phase II clinical trial evaluating zenocutuzumab in solid tumors positive for Neuregulin 1 (NRG1) gene fusions, reported manageable side effects and clinically meaningful efficacy—including a near doubling of p

Genespire, in collaboration with researchers at the San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), announced the publication of preclinical data supporting the potential of its liver-directed immune-shielded lentiviral gene therapy approach to treat methylmalonic ac

The meningococcal B vaccine is ineffective in gonorrhea prevention among men who have sex with men (MSM) at high risk of infection, according to findings from the world's largest randomized controlled trial (RCT) into possible efficacy published in the New England Journal of Medi

Scientists at the Department of Cell Biology of the University of Malaga have taken a step forward in the search for more effective treatments for pain with a new study that advances efforts to mitigate the addictive effects of morphine—one of the main drugs used for this purpose

Committee will meet in July to discuss peptides now sold in gray market despite limited evidence of safety and efficacyAdvisers to the Food and Drug Administration (FDA) will soon hold a meeting about whether to ease restrictions on access to some research peptides, a group of dr

A new collaborative study reports the discovery and application of a novel therapeutic strategy to selectively target EGFR and other kinases with controlled release in tumor microenvironments to improve therapeutic efficacy, with promising results. The research is published in Bi

Employees' biological clocks do more than determine when they reach for coffee; they fundamentally shape how, when and why people help each other at work. A study published in Organizational Behavior and Human Decision Processes introduces the concept of "time-extension self-effi