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A pilot study from Karolinska Institutet shows that immunotherapy may enable the stimulation of egg maturation in women with autoimmune POI (premature ovarian insufficiency)—a condition that usually leads to infertility. Three out of 10 women gave birth to healthy babies followin

Researchers from The University of Texas MD Anderson Cancer Center demonstrated that an artificial intelligence (AI)-based analysis of tumor biopsies can predict responses to immunotherapy in a study of patients with rare cancers, published in the Journal for ImmunoTherapy of Can

Cancer immunotherapy drugs known as immune checkpoint inhibitors (ICIs) can be miracle drugs for cancer patients, curing some and turning deadly disease into a manageable chronic condition in others. But these drugs work for only a subset of patients, with few indications why—a k

Researchers at the University of Pittsburgh, UPMC Hillman Cancer Center and the National Cancer Institute report that combining CAR T cell immunotherapy with a targeted radiopharmaceutical significantly improved tumor regression in preclinical models of neuroblastoma, a rare and

Women with cancer may not have the same chance of cure or quality of life as men—yet fewer than 2% of Australian cancer clinical trials report results separately for men and women. Women are also more likely to experience severe side effects from cancer treatment, including immun

Glioblastoma, the most aggressive malignant brain tumor in adults, remains one of the most challenging cancers to treat because of limited treatment options and a poor prognosis. Patient outcomes have remained largely unchanged in the past two decades, underscoring the need for i

A research team led by Professor Yoosoo Yang (Department of Integrative Biotechnology) of Sungkyunkwan University, in collaboration with the Korea Institute of Science and Technology (KIST) and Incheon National University, has developed a next-generation anticancer immunotherapy

Northwestern Medicine scientists have uncovered a biological mechanism that helps explain why most patients with glioblastoma fail to respond to immunotherapy, according to their study published in Nature Communications.

A leading-edge immunotherapy may extend survival for patients with one of the most aggressive forms of blood cancer, according to newly published five-year results from a major clinical trial in the Blood Journal. The clinical trial evaluated lisocabtagene maraleucel (liso-cel),

An experimental immunotherapy has beaten aggressive brain tumours in a handful of children, and a personalised version is now being tested on more patients

Researchers found that a rare liver cancer evades immunotherapy by luring immune T cells away from the tumor and trapping them in nearby fibrous tissue. An FDA-approved drug called AMD3100 freed those T cells to attack the cancer, significantly improving the effectiveness of immu

A research team at the University of Turku in Finland has developed a reliable laboratory model to study BAP1-deficient melanomas, which are a rare type of melanoma that evade the immune system once they have metastasized and are universally resistant to current state-of-the-art