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For patients struggling to breathe because of acute respiratory failure, clearing mucus from the airways is a routine part of treatment. Mucoactive agents are widely used for this purpose. But after years of clinical use, one question remains: Do mucoactive agents actually help?

Pseudomonas aeruginosa is an opportunistic pathogen that can cause acute and chronic infections. Responsible for many hospital-acquired infections, it is also a major concern for people with cystic fibrosis, whose lungs are clogged with thick mucus that promotes its growth.