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After amyloid plaques form, tau and alpha-synuclein pathology rises in mice
After amyloid plaques form, tau and alpha-synuclein pathology rises in mice
The aging brain frequently harbors multiple protein pathologies that contribute to Alzheimer's, Parkinson's and other neurodegenerative diseases. But how do these problematic proteins interact with each other, and could these interactions inform future therapies? Researchers at T
Amyloid-clearing treatment may curb tau buildup for years in Alzheimer's brain
An analysis of the brain of a deceased Alzheimer's disease (AD) clinical trial participant found that regions where an anti-amyloid therapy successfully cleared amyloid plaques showed little to no evidence of tau tangles, a hallmark of AD closely linked to neurodegeneration and c
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Game that reduces dementia risk may clear amyloid from men’s brains
Playing a mental speed-training game seems to help the brain clear a protein linked to Alzheimer’s disease in men, but may work in women through different mechanisms