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Blocking IL1RAP, a receptor that sits at a key control point in inflammatory signaling, can disrupt the tumor-driven inflammatory network that helps pancreatic cancer resist treatment, according to new research. Led by researchers at Sylvester Comprehensive Cancer Center, part of

Scientists from the University of Bath (UK) have shed new light on how Crohn's disease develops and why it affects people differently after finding new evidence of a link between a key immune system gene in the gut and signaling of the hormone estrogen.

Our cells rely on tightly regulated signaling pathways to control when they grow, divide and survive. When these regulatory systems are disrupted, cells can acquire the ability to grow uncontrollably and become cancerous. One of the most important cancer-related signaling molecul

The cells lining skin capillaries are constantly sending each other messages—tiny pulses of calcium that help regulate blood flow, sense physical forces and keep vessel walls intact. Scientists have known about this signaling for decades. What they didn't know, until now, is that

A new study published in Nature Communications identifies a molecular signaling pathway that contributes to the development of life-threatening aortic aneurysms and dissections in Marfan syndrome, a genetic disorder affecting connective tissue. The findings provide new insight in

Irritable bowel syndrome (IBS) is a common condition that affects more than 10% of the general population, causing recurrent abdominal pain, bloating, constipation and diarrhea. IBS is considered a disorder of gut-brain interaction, and previous research, including genetic resear

Northwestern Medicine scientists have uncovered a biological mechanism that helps explain why most patients with glioblastoma fail to respond to immunotherapy, according to their study published in Nature Communications.

A pauta traz uma atualização relevante e serve como base para a cobertura editorial. O recorte ajuda a contextualizar a pauta dentro de Economia.

Investors are looking forward to Samsung’s earnings and SK Hynix’s ADR listing, experts say. O recorte ajuda a contextualizar a pauta dentro de Carreira.

Kim Jong Un vows to equip North Korea's navy with nuclear weapons, signaling a strategic shift in military capabilities.

Reactive oxygen species (ROS) produced naturally during cellular metabolism often cause oxidative damage to cells. However, these molecules also play an important role in normal cellular signaling. While ROS are established as essential signaling molecules in various organisms, t

Researchers at the University of Bayreuth and Forschungszentrum Jülich have demonstrated that specific light-sensitive enzymes—so-called sensor histidine kinases (SHKs)—transmit their signal through a light-controlled change in asymmetry. With their new study, the researchers con