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Blocking IL1RAP, a receptor that sits at a key control point in inflammatory signaling, can disrupt the tumor-driven inflammatory network that helps pancreatic cancer resist treatment, according to new research. Led by researchers at Sylvester Comprehensive Cancer Center, part of

After a median follow-up of 10 years, more than one-third of patients with large B-cell lymphoma and nearly half of patients with follicular lymphoma who received a single infusion of tisagenlecleucel—the CAR T-cell therapy developed by Carl June, MD, that would go on to become t

The McGill University Health Centre (MUHC) is the first site in the world to launch a first-in-human phase 1 clinical trial evaluating a novel radioligand therapy for HER2-positive cancers, including certain types of breast cancer.

Leading CAR T cell therapy researchers have developed a human-in-the-loop artificial intelligence (AI) framework that centers scientists' expertise to find viable target antigens for CAR T cell therapy. The work was led by experts from the Perelman School of Medicine at the Unive

A Monash University-led study has found that an unusual pairing of two commonly used antibiotics can kill and stop the spread of resistance in a highly drug-resistant bacterium, Pseudomonas aeruginosa, which can cause life-threatening bloodstream infections, pneumonia and meningi

The therapeutic use of psychedelic drugs has attracted no shortage of media and scientific interest in recent years—and this is only likely to grow.

Researchers at Weill Cornell Medicine, Cedars-Sinai Medical Center and Roswell Park Comprehensive Cancer Center have developed genetically engineered CAR T cells that specifically target and kill bladder cancer cells. The study, published in the Journal of Experimental Medicine (

Behavioral therapy is just as effective as medication for Tourette syndrome. This is the finding of doctoral research conducted by clinical psychologist Jolande van de Griendt, who will receive her Ph.D. from Radboud University on July 3, 2026. "Medication is still often the firs

In a recent episode of British sitcom Amandaland, Anne Flynn turns to ChatGPT for help talking to her teenage son about sex. The episode frames this as "The Chat": the awkward parent-child conversation many adults dread.

Hereditary hearing loss affects millions globally, with mutations in the SLC26A4 gene among the most common genetic triggers, particularly across Asian populations. This condition leads to severe-to-profound deafness accompanied by inner ear malformations, such as an abnormally e

Psilocybin (the active ingredient of magic mushrooms) and MDMA (the active ingredient in ecstasy) are psychedelic or hallucinogenic drugs that can change how a person sees things and feels.

A large-scale analysis by an international research team, led by Bochum University of Applied Sciences, shows that nonsurgical treatments such as massage, exercise therapy or acupuncture for chronic back pain can alleviate symptoms—but usually only for a few weeks. Clinically sig