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Parkinson's disease is the second most common neurodegenerative disease worldwide after Alzheimer's disease and, according to the World Health Organization, one of the fastest-growing neurological disorders. Yet genetic research into the disease has so far relied almost exclusive

Synucleinopathies are a group of neurodegenerative disorders that include serious conditions such as Parkinson's disease and dementia with Lewy bodies. There are currently no cures for these disorders, and treatment is limited to mitigating symptoms. Recently, antibody-based ther

Sleep disorders may do more than leave people feeling tired. New research from Florida International University shows that sleep disorders are associated with structural changes in brain regions involved in attention, motivation and decision-making.

Strange "chimeric" RNA once thought to be the product of cancer is actually an important controller of women's health, including influencing their susceptibility to infectious disease and autoimmune disorders, new University of Virginia School of Medicine research suggests.

In autoimmune disorders, immune cells targeting "self" proteins are mistakenly activated, resulting in abnormal expansion and responsiveness. These disorders are known to reduce patients' quality of life over a prolonged period. This can be attributed to CD4+ T cells, which play

Researchers at the Nuffield Department of Primary Care Health Sciences, University of Oxford, have developed a new calculator that estimates a person's risk of developing serious muscle disorders from statins. The tool could help patients and clinicians make more informed decisio

Right ventricular dysfunction (RVD) is prevalent in 41.7% of patients with heart failure with preserved ejection fraction (HFpEF), according to a study published online June 10 in BMC Cardiovascular Disorders.

Major depressive disorder (MDD) is a psychiatric condition characterized by persistent feelings of sadness, a loss of interest in everyday activities, altered sleeping and/or eating patterns, low energy, and difficulty concentrating on tasks. While it is one of the most widesprea

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs), such as Ozempic or Wegovy, have revolutionized type 2 diabetes and weight-loss management, but they have also led to some unfortunate outcomes. A recent study in JAMA Psychiatry has raised concerns that GLP-1 medications may

A research team from National Taiwan University and the University of Oslo analyzed data on more than 1.3 million children across two countries, finding that an earlier European safety warning for valproate weakens to nonsignificance once underlying disease and other confounders

Exposure to extreme heat and cold is associated with an increased risk of emergency department (ED) visits among people living with dementia, according to preliminary research presented at the European Academy of Neurology (EAN) Congress 2026. The findings provide new evidence th

A sweeping global review led by researchers at the University of British Columbia has found that mRNA vaccines—now administered billions of times worldwide—are safe and highly effective at preventing infectious diseases like COVID-19, and have potential applications for a range o