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Dozens of research teams around the world are working to halt, treat and even prevent Alzheimer's disease, which silently develops in the brain for more than a decade before symptoms appear. Although recent years have brought important advances, researchers continue to search for

A new blood test may make it easier to detect the most dangerous forms of prostate cancer early. In a study from Karolinska Institutet, the Stockholm3 blood test detected more clinically significant cancer cases than the PSA test, without subjecting more men to unnecessary testin

In humans and other mammals, spinal cord injuries can be devastating, leading to permanent loss of movement, sensation and bladder control. When severed axons (the long fibers that carry messages between nerve cells) cannot regrow, a dense scar forms, preventing nerve signals fro

Researchers led by Universitätsmedizin Frankfurt and Goethe University Frankfurt have identified how particularly aggressive forms of lymphoma can be recognized. By combining genetic and proteomic analyses, the scientists identified biological characteristics of tumors, particula

Unlike accidental cell death, some cells can actively decide to die through a controlled process. This is called programmed cell death and can occur in different forms, including apoptosis and necroptosis. Cells use this process when they are damaged, stressed, becoming cancerous

A chemical called 6PPD-quinone (6PPD-Q), which forms when shaved-off tire particles come into contact with ozone, might interfere with the inner workings of brain cells, leading to Alzheimer's disease. Zhang and Zhang's new paper in the journal Open Medicine, "6PPD‑Quinone Exposu

Researchers at the University of Pittsburgh, UPMC Hillman Cancer Center and the National Cancer Institute report that combining CAR T cell immunotherapy with a targeted radiopharmaceutical significantly improved tumor regression in preclinical models of neuroblastoma, a rare and

DZNE researchers have uncovered a mechanism that determines why a neuron usually forms a single, long extension called an "axon"—a phenomenon that is fundamental to how our brain functions. Contrary to the common view that external cues drive axon formation, the team of scientist

Scientists have identified a promising new strategy to tackle one of the biggest obstacles in treating glioblastoma, one of the most aggressive forms of brain cancer: resistance to chemotherapy. The study shows that an experimental compound called BA-101 can restore the effective

Inhibiting menin, a protein that supports leukemia growth and is already targeted to treat some forms of leukemia, also holds promise for treating myeloproliferative neoplasms. A new study from scientists at St. Jude Children's Research Hospital showed that inhibiting menin signi

Research led by a University of Sydney medical student could enable earlier and more accurate diagnosis of behavioral variant frontotemporal dementia—one of the most commonly misdiagnosed forms of early-onset dementia, which can begin as early as a person's late 40s and is often

A leading-edge immunotherapy may extend survival for patients with one of the most aggressive forms of blood cancer, according to newly published five-year results from a major clinical trial in the Blood Journal. The clinical trial evaluated lisocabtagene maraleucel (liso-cel),