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Humans cannot fully heal spinal cord injuries. When the spinal cord is damaged, the body's immune system often spirals into chaos. This overwhelming inflammatory response creates permanent scar tissue that stops nerve cells from ever repairing themselves or their connections. Zeb

Lincoln researchers are the first to show that metabolites produced by certain gut bacteria can positively affect the body's immune response to cancer.

Researchers at Trinity College Dublin have discovered that microglia—the main immune cells of the brain—play a critical role in maintaining the stability of neuronal networks in Alzheimer's disease. Crucially, this suggests treatments that indiscriminately suppress these cells co

Low levels of replicating Epstein-Barr viruses might be the main driver of the autoimmune condition multiple sclerosis. This may mean that targeting them would be as effective as suppressing the immune system, with fewer side effects

Researchers at The University of Texas MD Anderson Cancer Center have created a comprehensive single-cell map of the tumor immune microenvironment in multiple myeloma and its precursor conditions. The study provided insights that may explain why patients with similar diagnoses of

A constant interplay takes place on the surface of the body between cells, the immune system and the skin microbiota. We do not notice it—until the balance is disturbed. Then it becomes clear that the outermost layer of the skin plays a crucial role in the well-being of the whole

Scientists from the University of Bath (UK) have shed new light on how Crohn's disease develops and why it affects people differently after finding new evidence of a link between a key immune system gene in the gut and signaling of the hormone estrogen.

Two new studies jointly published in Nature Communications reveal that certain species of fungi in the gut play a key role in the development of immune dysregulation and some pediatric allergic diseases—and may be promising targets for new therapies.

Researchers have identified a critical biological difference in how glioblastoma develops in male and female laboratory models, pinpointing an immune pathway that fuels tumor growth only in females. The study shows that the neurotransmitter GABA boosts the cancer-protecting activ

Systemic lupus erythematosus (SLE), the most common form of lupus, is an autoimmune disorder that occurs more frequently in women. Having multiple X chromosomes has been associated with an increased risk of developing lupus; however, the reason for this link is still not fully un

Researchers at Hospital for Special Surgery (HSS) have identified a specialized population of immune cells that plays a central role in driving abnormal tissue growth in rheumatoid arthritis (RA), offering new insight into disease progression and potential treatment strategies. T

In autoimmune disorders, immune cells targeting "self" proteins are mistakenly activated, resulting in abnormal expansion and responsiveness. These disorders are known to reduce patients' quality of life over a prolonged period. This can be attributed to CD4+ T cells, which play