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Análise de cérebro após tratamento mostra que a ação contra placas e proteínas ligadas à doença varia entre diferentes regiões cerebrais O post Nova autópsia revela pistas sobre por que medicamentos contra Alzheimer falham apareceu primeiro em Olhar Digital.

While France confirmed its first case of Ebola, reports of people successfully treated for the condition are also emerging from Mongbwalu, the epicentre of the epidemic in the eastern part of the DRC. Although successful treatments are sparking hope among teams on the ground, hea

Researchers at The University of Texas MD Anderson Cancer Center have created a comprehensive single-cell map of the tumor immune microenvironment in multiple myeloma and its precursor conditions. The study provided insights that may explain why patients with similar diagnoses of

Researchers at Hospital for Special Surgery (HSS) have identified a specialized population of immune cells that plays a central role in driving abnormal tissue growth in rheumatoid arthritis (RA), offering new insight into disease progression and potential treatment strategies. T

Alzheimer's disease is driven by a buildup of a toxic protein called Tau that kills neurons. As toxic Tau spreads to new regions of the brain, symptoms worsen and ultimately become fatal.

Cognitive decline in very old adults has been considered for decades to be an almost inevitable consequence of aging. In clinical practice, this has contributed to many memory problems in patients over age 80 being interpreted as a natural part of aging, without further investiga

Small loops of genetic material may be strong indicators of imminent Alzheimer's disease (AD) symptoms. In a new study published in Nature Medicine, researchers showed that elevated levels of certain circular RNAs (circRNAs) in the blood nearly tripled patients' risk of developin

Results of the ongoing eNRGy trial, a single-arm, multicenter, global Phase II clinical trial evaluating zenocutuzumab in solid tumors positive for Neuregulin 1 (NRG1) gene fusions, reported manageable side effects and clinically meaningful efficacy—including a near doubling of p

Researchers at VIB and KU Leuven, with international partners, have uncovered how fatty liver disease can fuel the most aggressive form of metastatic colorectal cancer. The findings, which appear in the journal Nature, not only explain why some patients face dramatically poorer o

Researchers at Tel Aviv University's Gray Faculty of Medical and Health Sciences have uncovered how a natural and essential immune system process can be hijacked to promote cancer progression. In a new study, the research team developed an advanced technology that enabled it to t

Researchers at the Icahn School of Medicine at Mount Sinai have found that patients with Parkinson's disease undergoing deep brain stimulation (DBS) show little to no Lewy pathology in the prefrontal cortex at the time of their DBS surgery, despite often having longstanding, clin

For patients with relapsed/refractory (R/R) chronic lymphocytic leukemia (CLL), adding pirtobrutinib to venetoclax-rituximab (PVR) yields improved progression-free survival (PFS) compared to venetoclax-rituximab (VR), according to a study presented at the annual congress of the E