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For decades, researchers have been trying to understand the biological roots of autism spectrum disorder (ASD), a common neurodevelopmental condition that shapes how people communicate, learn and interact with the world. One of the major hurdles is that the brain's neural network

The national survey of 2,100 bi+ people—which includes identities like bisexual, pansexual, queer and fluid—provides crucial information to inform better health policy and services.

For more than 150 years, fossils of Jurassic fish scattered across Europe's museums were studied and drawn by generations of scientists. However, when a paleontologist decided to shine an ultraviolet light on them, a hidden world lit up.

For the immune system to effectively combat pathogens, antibody responses must be precisely controlled. So-called follicular regulatory T cells (Tfr cells) play a key role in this process by limiting excessive immune responses and helping to maintain immune tolerance. Researchers

Major depressive disorder (MDD) is a psychiatric condition characterized by persistent feelings of sadness, a loss of interest in everyday activities, altered sleeping and/or eating patterns, low energy, and difficulty concentrating on tasks. While it is one of the most widesprea

The development of cancer is not a process triggered immediately by the emergence of an oncogenic mutation. There is growing evidence for the existence of an intermediate phase—hitherto poorly defined—in which mutated cells remain in a latent state, "accumulating the potential ne

Temporomandibular disorders (TMDs) are a group of more than 30 conditions that cause pain and dysfunction in the jaw. So what could a small tissue sample from a rat's knee have to do with treating them?

Biohub researchers have performed what they believe is the first genome-wide CRISPR study of primary human adult skin cells, then used an AI model to mine the results for overlooked drug targets for psoriasis. They found an unlikely candidate: the receptor for oxytocin, a hormone

Skeletal muscles—responsible for movement, joint stabilization and postural support—are highly metabolically active and heavily reliant on oxygen during physical activity. However, conditions such as high-intensity exercise or sustained exertion frequently expose skeletal muscles

Report uncovers biggest childbirth scandal in NHS history in which 520 mothers and babies suffered ‘potentially avoidable’ harm or diedHorrific failings led to 520 mothers and babies in Nottingham suffering harm or dying, sparking calls for a public inquiry into maternity care ac

In new images from NASA’s James Webb Space Telescope to celebrate its fourth science anniversary, a familiar galaxy transforms into something far richer, and far more complex, than ever seen before. Webb’s unprecedented sensitivity across near- and mid-infrared wavelengths cuts t

Researchers have identified "DNA switches" that become active as honeybee larvae grow into worker bees, offering new insight into the development of these important pollinators and the ecosystems they support.