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34,267 notícias encontradas para "impact"
Gene regulation map reveals treatment targets for heart failure
Gene regulation map reveals treatment targets for heart failure
Researchers from the University of California San Diego have created the most detailed map to date of how gene regulation breaks down in human heart failure, revealing how genes are controlled in specific cell types as the disease develops and pointing to potential new therapeuti
Cruise ship outbreak highlights need for clear communication on emerging disease threats
Cruise ship outbreak highlights need for clear communication on emerging disease threats
A small outbreak of a rare hantavirus on a cruise ship earlier this year captured worldwide attention and sparked concerns about a possible new pandemic. But according to a new University of Maryland School of Medicine (UMSOM) commentary published in JAMA Internal Medicine, the o
Brain immunity may undergo a major midlife overhaul linked to neuroinflammation
Brain immunity may undergo a major midlife overhaul linked to neuroinflammation
A new study indicates that the immune cell landscape of the hippocampus, a brain region critical for learning and memory, rapidly undergoes substantial remodeling beginning in midlife. This previously unrecognized shift suggests a potential mechanism by which aging may contribute
Quem quer ser maratonista precisa treinar quantas horas por dia?
Quem quer ser maratonista precisa treinar quantas horas por dia?
Prepare-se para a maratona: descubra o que a ciência diz sobre a duração ideal do treino e a importância da estratégia. O recorte ajuda a contextualizar a pauta dentro de Fitness.
From urinary tract infection to brain abscess: How bacterial subpopulations can spread to
From urinary tract infection to brain abscess: How bacterial subpopulations can spread to
Researchers from the University of Cologne, the German Center for Infection Research (DZIF), and the Broad Institute of Harvard and MIT present a clinical case in the New England Journal of Medicine that provides new insights into the evolution of bacterial pathogens and presents
Focused ultrasound may enhance chemotherapy, survival outcomes for pancreatic cancer
Focused ultrasound may enhance chemotherapy, survival outcomes for pancreatic cancer
A phase 2 clinical trial published in the European Journal of Cancer suggests that a novel form of focused ultrasound combined with standard FOLFIRINOX chemotherapy may improve tumor response and survival outcomes in patients with either borderline resectable pancreatic cancer or
Two ways to read a genome: Body-wide, single-cell atlas maps DNA folding and methylation t
Two ways to read a genome: Body-wide, single-cell atlas maps DNA folding and methylation t
Every cell in the human body carries the same 3 billion letters of DNA, yet a neuron, a heart muscle cell and a pancreatic beta cell each use that shared code to do entirely different jobs. How cells pull off this trick comes down to epigenetics—chemical tags and three-dimensiona
New PPAR therapies could slow fibrosis in primary biliary cholangitis
New PPAR therapies could slow fibrosis in primary biliary cholangitis
Primary biliary cholangitis is a rare autoimmune disease that affects the liver and can progress to cirrhosis. It occurs when the immune system attacks the small bile ducts within the liver. As a result, bile builds up, leading to inflammation and progressive liver damage. Althou
New strategy could prevent T cell exhaustion and boost immunotherapy
New strategy could prevent T cell exhaustion and boost immunotherapy
A major pillar of cancer immunotherapy involves stimulating T cells, the specialized killers of the immune system, to attack tumors. But this strategy has been undermined by the tendency of T cells to tire out before finishing the job. When the cells reach a fatigued stage—called
Burden of myocardial dysfunction elevated for individuals with psoriasis
Burden of myocardial dysfunction elevated for individuals with psoriasis
Individuals with psoriasis have a higher burden of myocardial dysfunction, independent of cardiometabolic risk, according to a study published online July 17 in the Journal of the European Academy of Dermatology and Venereology.
Overlooked brain protein tied to epilepsy yields first inhibitors in early experiments
Overlooked brain protein tied to epilepsy yields first inhibitors in early experiments
Scientists at the Icahn School of Medicine at Mount Sinai have uncovered the first high-resolution structure of NBCn2, a brain protein linked to epilepsy, autism spectrum disorder and other neurological conditions, and developed the first compounds capable of inhibiting its activ
Research reveals persistent racial disparities in stroke treatment and outcomes
Research reveals persistent racial disparities in stroke treatment and outcomes
Three studies presented at the Society of NeuroInterventional Surgery's (SNIS) 23rd Annual Meeting found that racial, geographic and socioeconomic disparities continue to influence stroke treatment and outcomes across the United States. Together, the findings suggest that while a