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Kidney cancer gene reveals an unexpected weakness and a new path for treatment
A common genetic mutation that helps some kidney cancers survive may also expose an unexpected weakness, one that MUSC Hollings Cancer Center researchers hope to transform into a new treatment strategy. In a study published in Cancer Research, Aguirre de Cubas, Ph.D., and colleag
Foto: Anna Tarazevich / Pexels
Newfound biomarkers may someday help clinicians better detect—and possibly cure—Lyme disea
Lyme disease can be easiest to treat in its earliest stages, but current tests often miss infections during that critical window and cannot tell whether bacteria are still present or were cleared years ago. New research led by Tufts University School of Medicine suggests that a g
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Breast milk gives certain gut bacteria a head start
Breast milk helps shape the gut microbiota for longer than previously thought. Researchers from DTU and Rigshospitalet have discovered that sugars in breast milk, which are nondigestible by the infant—so-called human milk oligosaccharides (HMOs)—influence which bacteria thrive in
AI-guided pathology analysis can help predict immunotherapy response in rare cancers
Researchers from The University of Texas MD Anderson Cancer Center demonstrated that an artificial intelligence (AI)-based analysis of tumor biopsies can predict responses to immunotherapy in a study of patients with rare cancers, published in the Journal for ImmunoTherapy of Can
New mechanism behind breast cancer metastasis uncovered
New mechanism behind breast cancer metastasis uncovered
Researchers at Umeå University show that the protein METTL3 helps breast cancer cells spread. By regulating the release of molecules, METTL3 makes it easier for tumors to invade surrounding tissue and form metastases. The discovery reveals a previously unknown function of METTL3
Nutrition apps can help build healthy habits. For some users, their gaming features carry
Green means go, red means stop. Trophies or confetti come with good performance, and people who fall behind get nudged to do better.
Repurposed epilepsy drug could be used to boost vaccine protection among elderly
A drug commonly used to treat epilepsy could be repurposed to significantly boost the response to vaccines in humans, helping protect those for whom the vaccine is less effective, such as older adults or immunocompromised people. A Cambridge-led team showed that the drug more tha
Cryo-EM helps identify the mechanisms of dental plaque formation
Periodontal (gum) disease is one of the most prevalent diseases worldwide, caused by the bacterium Porphyromonas gingivalis (P. gingivalis). In Japan alone, approximately 80% of adults 30 and older are affected or considered at risk.
Treating Duchenne muscular dystrophy before symptoms emerge may improve motor function, cl
At Binghamton University, researchers were among the first to find ways to help patients with Duchenne muscular dystrophy (DMD) through the development of an effective drug. Now, they are continuing that work, looking to reduce its effects even earlier.
Melatonin may ease chronic pain, study finds
A sleep supplement widely used to treat insomnia could help reduce reliance on some of the most common and potentially harmful pain medications, new research from the University of Sydney suggests.
Lower thresholds may explain rise in young people's service use for mental health issues
Lower thresholds may explain rise in young people's service use for mental health issues
Lower thresholds for seeking medical help and/or changes in diagnostic practice, rather than a true increase in worsening psychological ill health, may help explain the rise in young people's primary care service use for mental health issues, suggest the findings of a large, long
COVID-19 vaccine boosters may help protect against future animal coronaviruses, research s
COVID-19 vaccine boosters may help protect against future animal coronaviruses, research s
COVID-19 vaccine boosters not only protect against SARS-CoV-2—the virus behind the most recent pandemic—but may also help protect against some future coronaviruses that risk spreading from animals to humans, Cambridge researchers have shown.