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Biomarker-guided care to improve antidepressant response rates and reduce trial-and-error
For millions of people living with depression, finding an effective treatment can feel like a long and uncertain journey. Patients often spend months trying different medications, enduring side effects and persistent symptoms while waiting to discover whether a prescription will
HIV vaccine triggers broadly neutralizing antibodies in 44% of primates
A new HIV vaccine developed by La Jolla Institute for Immunology (LJI), Scripps Research scientists and IAVI has the potential to protect humans from developing HIV infection and AIDS. This HIV vaccine is the first to generate a high number of "broadly neutralizing" virus-fightin
Mutations let JC polyomavirus evade antibodies, offering clues for vaccines and treatments
In people with severely compromised immune systems, JC polyomavirus can trigger an untreatable, often fatal brain disease. An international research team has identified how virus mutations can strategically interfere with how human antibodies recognize the virus, allowing it to e
Oyster meat may provide a sustainable solution for intestinal inflammation
Oyster meat may provide a sustainable solution for intestinal inflammation
Ongoing research provides evidence that readily available and sustainable oyster meat extract may have powerful anti-inflammatory effects on human intestinal cells.
Study linking microgravity and space radiation to accelerated aging could yield therapies
Study linking microgravity and space radiation to accelerated aging could yield therapies
What happens to the human body in space may help scientists create new anti-aging therapies. UCF's Michal Masternak and his team have identified molecular changes in the liver that happen when space travelers experience radiation and microgravity. These changes—that resemble acce
Novel antibody-drug conjugate eliminates residual cancer cells in majority of patients wit
Researchers at The University of Texas MD Anderson Cancer Center were able to eradicate measurable residual disease (MRD) in B-cell acute lymphoblastic leukemia (ALL) patients, a critical step in improving long-term survival outcomes, by treating them with the antibody-drug conju
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Antibiotic prescribing remains above 95% for uncomplicated diverticulitis
Antibiotic prescribing has remained above 95% for uncomplicated diverticulitis at Veterans Affairs facilities, according to a study published online June 23 in Annals of Internal Medicine.
Chlorhexidine blend wipes out 99.9% of Candida parapsilosis cells in lab tests
A 0.5% alcohol-based chlorhexidine antiseptic, combined with the natural organic compounds eugenol and menthol, can eliminate 99.9% of Candida parapsilosis cells. This fungus is one of the leading causes of infections in hospital settings, such as intensive care units (ICUs).
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Commonly used drugs show small benefit for long COVID fatigue
Over-the-counter antihistamines and a prescription anti-inflammatory drug both have a small benefit in reducing long COVID fatigue among people receiving care from specialist long COVID clinics, according to new findings from a large clinical trial led by UCL and UCLH.
Medicare prescriptions for Wegovy jumped after approval for heart disease
Medicare prescriptions for Wegovy increased sharply after the program started covering the anti-obesity medication to prevent heart problems, but just a fraction of beneficiaries likely eligible received the treatment, according to new research published in the American Journal o
Sexually transmitted diarrhea spreading rapidly among some networks of gay men in the UK,
Variants of sexually transmitted Shigella—a bacterial infection that causes bloody or prolonged diarrhea and can lead to severe dehydration—are causing more disease and becoming increasingly antibiotic-resistant among sections of the U.K.'s LGBTQ+ community, a new Cambridge study
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How birth method and antibiotics may shape babies' gut bacteria
A new systematic review has found that both the way a baby is born and exposure to antibiotics around the time of birth could be linked to differences in the development of the infant gut microbiome. The review also found that exclusively breastfeeding babies born by cesarean sec