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Online therapy lowers depression and anxiety for dementia caregivers after six months
A University of East Anglia project to help caregivers looking after people with dementia has been hailed a success. Researchers created a digital therapy platform for use on mobile devices or computers and tested it with almost 500 volunteers.
Economic evaluation supports prophylactic naldemedine for opioid-induced constipation in c
Although opioids remain indispensable for pain relief in patients with advanced cancer, their use frequently results in OIC, which can substantially reduce quality of life and, in some cases, compromise the continuation of optimal pain management. Naldemedine, a peripherally acti
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Artemisinin resistance is rising in East Africa—leaving anti-malarials at risk of failure
Resistance to the main drug in front-line malaria treatments is becoming more widespread across East Africa, according to new research by Imperial College London. The study, published in The Lancet Infectious Diseases, maps the rise in artemisinin resistance in the region and sug
How AI accelerates radiopharmaceutical drug discovery, optimizes personalized dosimetry
A feature News and Perspectives story on technological advances in oncology was published in Journal of Medical Internet Research. Authored by JMIR Correspondent Benedette Cuffari, "AI-Designed Radiopharmaceuticals: How Machine Learning Is Redefining Precision Cancer Therapy" rep
Engineers develop AI tool to design peptides that turn signals on or off
To develop new and better peptides, the short amino acid strings behind medicines like GLP-1 drugs, researchers have used AI to generate candidates and to predict their properties.
Inhibiting protein to treat myeloproliferative neoplasms shows preclinical promise
Inhibiting menin, a protein that supports leukemia growth and is already targeted to treat some forms of leukemia, also holds promise for treating myeloproliferative neoplasms. A new study from scientists at St. Jude Children's Research Hospital showed that inhibiting menin signi
Night owls eat later, choose less nutritious food, carry more belly fat and show higher me
For generations, early to bed and early to rise was seen as the blueprint for a healthy life, and any departure from it was often considered unhealthy. Scientists, however, have discovered that whether someone is an early bird who wakes up early and starts the day with energy or
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Scientists improve the analgesic efficacy of morphine
Scientists at the Department of Cell Biology of the University of Malaga have taken a step forward in the search for more effective treatments for pain with a new study that advances efforts to mitigate the addictive effects of morphine—one of the main drugs used for this purpose
Bacteria from gum disease may cause inflammation, harden heart valves
Gum disease bacteria may spur calcium buildup in the heart's aortic valve, leading to a common and serious heart valve disease, according to preliminary, independent research presented at the American Heart Association's Basic Cardiovascular Sciences Scientific Sessions 2026, hel