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Researchers at Umeå University show that the protein METTL3 helps breast cancer cells spread. By regulating the release of molecules, METTL3 makes it easier for tumors to invade surrounding tissue and form metastases. The discovery reveals a previously unknown function of METTL3

Cancer cells are quick to develop resistance to anti-tumor drugs. New research by scientists from the University of California, Davis, shows how cancers adapt to evade a class of anti-tumor drugs called BET inhibitors and offers hope for more effective therapies.

A study conducted by the Sant Pau Research Institute (IR Sant Pau) and Hospital de Sant Pau has identified for the first time in living individuals a brain pattern related to the tau protein that changes according to the stage of Huntington's disease. This discovery opens the doo

Breakthrough research led by scientists in Manchester has identified a new drug combination that could improve outcomes for thousands of patients with lung cancer driven by a rare type of KRAS mutation, offering hope for patients worldwide with this difficult-to-treat subtype of

A protein produced by gut immune cells orchestrates both immune protection against pathogens and immune tolerance of gut bacteria, according to a study led by Weill Cornell Medicine investigators. The discovery illuminates the complex biology of the gut immune system and could le

Beyond its importance for scientific discovery, representation in health research directly influences health care planning, policy development and resource allocation.

Chronic and viral infections can literally exhaust certain key cells in the immune system from a constant barrage of attacks. But a new pair of papers by scientists at the Hackensack Meridian Center for Discovery and Innovation (CDI) points to a way to understand how this exhaust

Researchers at the University of Gothenburg have identified a key protein that allows the virus that causes genital herpes to get into the nervous system. The discovery, made in experiments on mice, could pave the way for future vaccines against the disease. The study is publishe

Researchers at the University of British Columbia have identified a new form of hereditary prostate cancer that, while rare, can cause aggressive disease at a young age. The discovery paves the way for genetic testing programs that could help identify at-risk families and support

Rat disease models have played an integral role in scientific discovery and cancer research, including Nobel Prize–winning work from Charles Huggins on hormone therapy for prostate cancer in 1966. However, technical challenges in genetic engineering of rat models have limited the

A feature News and Perspectives story on technological advances in oncology was published in Journal of Medical Internet Research. Authored by JMIR Correspondent Benedette Cuffari, "AI-Designed Radiopharmaceuticals: How Machine Learning Is Redefining Precision Cancer Therapy" rep

Most women are aware that fertility declines dramatically with age. This is mainly due to the gradual loss of eggs and follicles from the ovaries, leading to infertility, irregular cycles and ultimately menopause.