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Chronic kidney disease (CKD) is common, largely silent and serious. Most people who have the condition do not realize they have it, while it sharply raises the risk of heart attacks, strokes, kidney failure and early death. Over the past decade, the share of American adults livin

Women diagnosed early in pregnancy with a fetus lacking adequate kidney function to make the urine that serves as vital amniotic fluid have long faced virtually no chance of the fetus's survival after birth.

Resistance to the main drug in front-line malaria treatments is becoming more widespread across East Africa, according to new research by Imperial College London. The study, published in The Lancet Infectious Diseases, maps the rise in artemisinin resistance in the region and sug

Egg cells missing a key protein may be more likely to end up with the wrong number of chromosomes, but an mRNA injection that helps the cells make the protein reduces the problem

Report by Commons committee says government has failed to make concrete changes after recent security failuresBritain’s museums and galleries are being left vulnerable to thefts and cyber-attacks that could put priceless collections at risk, MPs have warned.A report by the public

UK watchdog gives King & King severe reprimand for failing ‘to identify clear self-interest’ when conducting auditsBusiness live – latest updatesThe UK’s accounting watchdog has fined and temporarily banned a tiny audit firm for “egregious” failures and “widespread deficiencies”

Spending watchdog says high-speed rail project must be put on stable footing to avoid repeat of costly past failuresRevised plans for HS2 should not be put into action until the government is confident they can be delivered, according to the public spending watchdog.The project t

The £45bn scheme to link cities across north of England with new or upgraded lines has no convincing or properly costed plan, committee saysBuilding Northern Powerhouse Rail (NPR) risks repeating the failures of HS2 with “no convincing plan” to deliver it within a £45bn budget, a

Exclusive: £20bn of ‘potential’ £30bn AI investment touted by UK ministers appears to have been hypotheticalIt was to be the biggest undertaking in Britain for OpenAI, the company behind ChatGPT. Stargate UK – a multibillion-pound UK datacentre project – would represent “a major

Exclusive: Latest Guardian revelation about gift from cryptocurrency tycoon comes as Reform UK leader forces byelectionThe £5m gift to Nigel Farage by a cryptocurrency billionaire was reported to the National Crime Agency by bankers who were concerned it may have been laundered m

Regulator found ‘unacceptable’ breaches in water company’s handling of drainage and sewage networkBusiness live – latest updatesThe water company Severn Trent has been spared a fine by the sector regulator over “serious and unacceptable breaches” in its handling of wastewater and

Strategic Petroleum Reserve stockpiles are precariously low and have been hit by major equipment failures, leaks and spills, according to a government report.