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The human brain contains billions of neurons, specialized nerve cells that communicate with each other via electrical and chemical signals. Every neuron is made up of its body (i.e., soma), where most cellular processes occur; a long projection called an axon that sends signals t

The aging brain frequently harbors multiple protein pathologies that contribute to Alzheimer's, Parkinson's and other neurodegenerative diseases. But how do these problematic proteins interact with each other, and could these interactions inform future therapies? Researchers at T

GLP-1 agonists have become popular treatments for weight loss and type 2 diabetes, and newer studies suggest other health benefits as well. Findings from experiments on mice, published in the Journal of Virology, suggest that the drugs may offer benefits to another patient popula

Over the past decades, some medical researchers and neuroscientists have been exploring the possible therapeutic effects of psychedelic compounds, such as lysergic acid diethylamide (LSD) and psilocybin. These are substances that act on serotonin receptors in the brain and can al

Oxygen isn't always a good thing. Of course, people—and most organisms—cannot live without it. But oxygen can also be quite toxic and lead to profound health consequences.

Researchers at the University of Gothenburg have identified a key protein that allows the virus that causes genital herpes to get into the nervous system. The discovery, made in experiments on mice, could pave the way for future vaccines against the disease. The study is publishe

By freezing your own healthy blood stem cells in your 20s, thawing them and undergoing a stem cell transplant in your 40s or 50s, it might be possible to rejuvenate your blood-forming and immune systems. Science fiction? At least it works when old mice receive healthy blood stem

Researchers at the University of Tsukuba have identified small nuclear fragments known as micronuclei while studying neurons in aged mice. They demonstrated that microglia—the brain's resident immune cells—take up these micronuclei, leading to changes in microglial morphology and

Repeated alcohol intoxication or exposure to stress appears to change how adolescent brains respond to danger. These changes persist into adulthood. In a study published in Alcohol: Clinical and Experimental Research, adolescent mice repeatedly exposed to alcohol or stress were l

Older mice that received a faecal microbiome transplant from younger animals went on to have improved brain plasticity, which suggests their brains could overcome a neurological condition that is typically successfully treated only in childhood

We used to think post-menopausal ovaries sat inert in the body, but evidence from mice suggests they may instead turn into an organ with a role in inflammation

Various issues – including a rodent infestation and mould – have left the historic, sprawling Ottawa estate empty10 Downing Street has two things: mice and a chief mouser. For more than a decade, an officially recognized feline has kept the residence’s rodent infestation to a min