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Early detection and treatment of congenital cerebral ventriculomegaly (CCV)—when a fetus's fluid-filled brain ventricles swell due to a condition called hydrocephalus—can help clinicians prevent developmental or neurological disabilities in affected infants. New research led by i

A research team led by Minyoung Lee and Sunggyu Park of The Korea Institute of Materials Science (KIMS) Bio & Health Materials Research Division has developed a plasmonic-based liquid biopsy platform capable of ultrasensitive detection of KRAS mutations in the blood and urine of

Walk into a crowded coffee shop, and what catches your eye as you take in the scene could say as much about you as the spirals on your fingertips or the mutations in your DNA. Eye movements are so unique, in fact, that they could be used to identify you through objects that have

Mutations to the protein SPOP are widespread in cancer, yet many remain poorly understood. To address this gap, St. Jude Children's Research Hospital scientists obtained structures of SPOP in both the presence and absence of these mutations. Their work captured the fine balance b

For decades, researchers studying myotonic dystrophy type 1 (DM1) have focused on the disease's underlying genetic cause: a mutation that produces a toxic form of RNA, disrupting the normal processing of thousands of genetic messages inside cells. While scientists have known this

A study of long-lived families has identified rare genetic variants that may help people stay healthier for much longer as they age. One standout mutation appears to temper inflammation, potentially delaying disease and extending years of healthy living.

Scientists found that one tiny genetic change can completely alter how a coronavirus behaves in different species. Comparing SARS-CoV-2 with a closely related bat-only virus, they showed that a single amino-acid difference affects whether the immune system fights back or gets sup

Beneath the surface of soybean fields, an invisible threat is costing farmers billions. Now, researchers at the University of Missouri are uncovering how nature itself may hold the key to fighting back. The soybean cyst nematode—a microscopic worm that attacks plant roots and sip

For every King Arthur or Roland, whose adventures readers can still enjoy today, another hero of ancient literature may have been lost forever. Before the printing press, texts were copied manually. This process introduced errors and innovations. Like mutations in the replication