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56 notícias encontradas para "phase"
Inhaled analgesia is as effective as morphine for early pain relief, study shows
Treating pain while in the field can be very demanding. Researchers have finally identified an effective alternative for providing pain relief during the earliest phase of prehospital care, when establishing intravenous access can be difficult. The study is published in The Lance
Radioligand therapy significantly prolongs progression-free survival in metastatic GEP-NET
Results of the Phase III COMPETE clinical trial show that the targeted radiotherapeutic agent [177Lu]Lu-edotreotide significantly prolonged progression-free survival in patients with metastatic gastroenteropancreatic neuroendocrine tumors (GEP-NETs) compared with targeted therapy
First randomized controlled trial shows promise of a ketogenic diet in psychotic disorders
First randomized controlled trial shows promise of a ketogenic diet in psychotic disorders
Published today in Schizophrenia Bulletin, a first-of-its-kind randomized controlled trial (RCT) from researchers at the University of California, San Francisco (UCSF), adds to growing literature on the potential benefit of a ketogenic diet for treating psychotic disorders. The s
New clinical data advances stem cell-based cell therapy for Parkinson's disease
New clinical data from the STEM-PD Phase I/II clinical trial have been presented at the ISSCR 2026 Annual Meeting. The study reports 12-month outcomes evaluating a cryopreserved, off-the-shelf dopaminergic progenitor cell product derived from human pluripotent stem cells for the
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Data highlight progress toward personalized stem cell therapy for Parkinson's disease
Interim clinical findings from the first Phase I/IIa trial using autologous-induced pluripotent stem cell (iPSC)-derived dopamine neuron precursor cells, along with the novel quality-control tools developed to manufacture these individualized therapies, have been presented by Jea
Huntington's treatment quest reaches first pluripotent stem cell trial, with safety now un
An update on the first clinical trial evaluating a pluripotent stem cell-derived neural stem cell therapy for Huntington's disease was presented at the ISSCR 2026 Annual Meeting. The Phase Ib/IIa REGEN4HD study represents a significant translational milestone following years of p
Researchers uncover hormone link between gut and brain in anorexia nervosa
Researchers uncover hormone link between gut and brain in anorexia nervosa
People with anorexia nervosa have unusually high levels of a hormone called LEAP2 in their blood when they are in the acute phase of the disorder, according to research presented at the Federation of European Neuroscience Societies (FENS) Forum 2026. Patients with the highest lev
Forget GLP-1s—GLP-3s show promise in phase 3 weight loss and diabetes trial
Forget GLP-1s—GLP-3s show promise in phase 3 weight loss and diabetes trial
Phase 3 clinical trial results (TRANSCEND-T2D-1) published in The Lancet report that retatrutide, an investigational once-weekly injection for diabetes management, can significantly improve blood sugar levels and lead to substantial weight loss in people with Type 2 diabetes. The
Hepatitis E viruses mutate early during infection
Knowing how viruses change in the initial weeks of an infection can provide important information about their adaptability. Researchers from the Departments of Molecular & Medical Virology and Translational & Computational Infection Research at Ruhr University Bochum, Germany, ha
Ibuprofen safely dampens inflammatory markers in 28-patient drug-resistant tuberculosis tr
The Experimental Tuberculosis Unit (UTE) at the Germans Trias i Pujol Research Institute (IGTP) has published in Nature Communications the results of a phase IIa pilot clinical trial assessing ibuprofen as a host-directed therapy in patients with pre-extensively drug-resistant tu
Genetically engineered Bifidobacterium shows potential for oral delivery of cancer vaccine
A novel oral vaccine platform using genetically engineered Bifidobacterium could enhance anti-tumor immunity. In an exploratory Phase I clinical study, the vaccine was well tolerated and generated immunologic and clinical findings that warrant further investigation. The results a
US-India trade deal: The key sticking points
US-India trade deal: The key sticking points
Both India and the US have signaled that the first phase of a landmark trade deal is close. DW looks at the main challenges in getting a deal past the finish line.