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A genetic difference carried by nearly one in three people may increase the risk of severe COVID-19 and lung fibrosis by disrupting the function of a previously unknown protein, according to a new study published in Nature Communications.

Researchers at Mayo Clinic have uncovered a previously hidden step in how the immune system prepares to fight cancer, a discovery that could help scientists develop more effective and longer-lasting cancer immunotherapies.

In a recent study published in Nature Communications, researchers at Karolinska Institutet report that the molecular machinery responsible for cellular energy conversion is more interconnected than previously understood, shedding light on how mitochondria adapt under stress.

Researchers at National Jewish Health have uncovered a previously unknown mechanism that helps drive inflammation in allergic asthma, offering new insight into how the disease develops and potentially revealing new targets for future therapies.

Breast milk helps shape the gut microbiota for longer than previously thought. Researchers from DTU and Rigshospitalet have discovered that sugars in breast milk, which are nondigestible by the infant—so-called human milk oligosaccharides (HMOs)—influence which bacteria thrive in

Researchers at Umeå University show that the protein METTL3 helps breast cancer cells spread. By regulating the release of molecules, METTL3 makes it easier for tumors to invade surrounding tissue and form metastases. The discovery reveals a previously unknown function of METTL3

Results of the ongoing eNRGy trial, a single-arm, multicenter, global Phase II clinical trial evaluating zenocutuzumab in solid tumors positive for Neuregulin 1 (NRG1) gene fusions, reported manageable side effects and clinically meaningful efficacy—including a near doubling of p

New research led by Mass General Brigham investigators suggests that the Bacillus Calmette-Guérin (BCG) vaccine—which is delivered through the skin to prevent tuberculosis—may remodel the human brain's immune environment, offering a potential biological explanation for previously

Northwestern Medicine scientists have discovered that one of the body's most fundamental biological processes—how red blood cells are made—works differently in humans than previously thought, according to a new study published in Nature Genetics. The findings overturn decades of

Researchers at the Mount Sinai Tisch Cancer Center have identified a previously underrecognized folate deficiency that may cause severe anemia in some patients receiving PARP inhibitors, a widely used class of targeted cancer therapies. Their findings, published in the latest iss

People with endometriosis have a distinct pattern of hormones that could be identified by a blood test, with the potential to revolutionize diagnosis of the condition, research suggests. Scientists have found that those with endometriosis have differences in a previously overlook

One of the uncomfortable truths about multiple sclerosis is that the part of the brain likely to reveal the most about the disease and how a patient will be affected has been mostly invisible to clinicians.