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The aging brain frequently harbors multiple protein pathologies that contribute to Alzheimer's, Parkinson's and other neurodegenerative diseases. But how do these problematic proteins interact with each other, and could these interactions inform future therapies? Researchers at T

The fever experienced by people with malaria exposes parasites to high temperatures within blood cells. This heat can lead to the accumulation of damaged proteins inside the parasite and trigger protective mechanisms against thermal stress.

Researchers at Weill Cornell Medicine and Birkbeck, University of London, have identified a site where a commonly used anesthetic binds to sodium ion channels, revealing a molecular mechanism that may explain how these drugs dampen communication between neurons. Ion channels are

An analysis of tooth proteins suggests all 23 Homo naledi individuals found in the Rising Star cave in South Africa were female, which strengthens the case that they were placed there deliberately

Marine bristle worms have jaws made from a mix of proteins and metal ions that may constitute a whole new kind of material, with possible applications in engineering

Scientists at Baylor College of Medicine may have uncovered a promising new way to combat Alzheimer’s and Parkinson’s disease. Instead of trying to stop Tau and alpha-synuclein proteins from gathering into tiny droplets inside brain cells, the researchers found that tubulin—the p

Ice formation can damage biological samples, tissues and materials during freezing and thawing. In nature, specialized molecules known as ice-binding proteins prevent ice crystals from growing too large, helping organisms survive in extreme cold. Scientists have long tried to rep

A new algorithm could drive breakthroughs in understanding cancer, Alzheimer's disease and other potentially fatal conditions. Researchers from the University of Waterloo developed the machine-learning algorithm, called RNovA, to detect changes in the proteins in human cells. The

Cryo-electron microscopy (cryo-EM) can help scientists determine the three-dimensional structure of proteins in unprecedented detail. Jacques Dubochet, former group leader at EMBL, shared the 2017 Nobel Prize in chemistry with Joachim Frank and Richard Henderson for the developme

A delivery system that uses lipid nanoparticles to sneak proteins into cells can accomplish the same feat by smuggling therapeutic antibodies, new research has found.

Scientists have extracted and analyzed the first-ever ancient proteins from the fossils of Homo naledi, revealing a potential all-female burial site. The study, published in the journal Cell, raises the possibility that South Africa's famous Rising Star Cave system could represen

How the proteins in our bodies bind together to form protein complexes plays a critical role in numerous cell functions—staving off diseases, for instance, or transporting ions across cell membranes. A better understanding of how they bind could lead to new medicines and possibly