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Researchers at Cima and Clinica Universidad de Navarra have identified new molecular mechanisms underlying multiple myeloma. This type of hematologic cancer, which affects the bone marrow, is characterized by its resistance to treatment, leading to relapses in patients. The resea

Cancer cells are quick to develop resistance to anti-tumor drugs. New research by scientists from the University of California, Davis, shows how cancers adapt to evade a class of anti-tumor drugs called BET inhibitors and offers hope for more effective therapies.

Mayo Clinic researchers have created a detailed map of the pulvinar, a deep brain region that could help doctors more precisely target brain stimulation therapies for people with drug-resistant epilepsy.

Globally, nearly 1 in 3 pregnant women experience depression, with most receiving no treatment. When they do get support, they're often steered toward talking therapies such as cognitive behavioral therapy (CBT) or mindfulness as the default option. A comprehensive review of diff

Cancer immunotherapy drugs known as immune checkpoint inhibitors (ICIs) can be miracle drugs for cancer patients, curing some and turning deadly disease into a manageable chronic condition in others. But these drugs work for only a subset of patients, with few indications why—a k

Researchers at the Mount Sinai Tisch Cancer Center have identified a previously underrecognized folate deficiency that may cause severe anemia in some patients receiving PARP inhibitors, a widely used class of targeted cancer therapies. Their findings, published in the latest iss

Parkinson's disease (PD) is the second most common form of neurodegenerative disease and afflicts more than 10 million people worldwide. While current therapies address disease symptoms, they do not prevent the underlying neurodegeneration that drives the disease.

What happens to the human body in space may help scientists create new anti-aging therapies. UCF's Michal Masternak and his team have identified molecular changes in the liver that happen when space travelers experience radiation and microgravity. These changes—that resemble acce

A new study published in JMIR XR and Spatial Computing demonstrates that the way virtual reality therapeutics (VRx) are introduced to patients is a critical factor in how successfully they adopt the technology. The randomized feasibility pilot study builds on growing evidence tha

The aging brain frequently harbors multiple protein pathologies that contribute to Alzheimer's, Parkinson's and other neurodegenerative diseases. But how do these problematic proteins interact with each other, and could these interactions inform future therapies? Researchers at T

Interim clinical findings from the first Phase I/IIa trial using autologous-induced pluripotent stem cell (iPSC)-derived dopamine neuron precursor cells, along with the novel quality-control tools developed to manufacture these individualized therapies, have been presented by Jea

The Blood and Tissue Bank is studying how to therapeutically manufacture and use a type of nanoparticles released by the body's cells to communicate with one another, in one of the most promising fields of research for the therapies of the future. New medicines and advanced thera