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Primary CNS lymphoma is a rare cancer that arises from malignant white blood cells. Affected individuals develop tumors in the brain and, more rarely, in the spinal cord, the eyes or within the cerebrospinal fluid. These lymphomas can occur in people with weakened immune systems,

According to the Cleveland Clinic, a quarter of cancer deaths can be attributed to one source: cachexia. Cachexia is a syndrome that accompanies underlying chronic illness and causes unwanted muscle and fat loss, reducing quality of life and sometimes even limiting treatment opti

Researchers led by Universitätsmedizin Frankfurt and Goethe University Frankfurt have identified how particularly aggressive forms of lymphoma can be recognized. By combining genetic and proteomic analyses, the scientists identified biological characteristics of tumors, particula

Hiroshima University researchers have demonstrated a proof of concept for the mass production of genome-edited T cells that can be used to treat malignant tumors, using a genetic engineering technique called Platinum TALEN.

A novel vaccination strategy against certain malignant brain tumors could fundamentally improve treatment for patients. Researchers from the German Cancer Research Center (DKFZ), Mannheim University Medical Center, Heidelberg University Hospital and numerous partner institutions

Results of the Phase III COMPETE clinical trial show that the targeted radiotherapeutic agent [177Lu]Lu-edotreotide significantly prolonged progression-free survival in patients with metastatic gastroenteropancreatic neuroendocrine tumors (GEP-NETs) compared with targeted therapy

A new "tumor-on-a-chip" model is giving scientists a live look at how pancreatic cancer can recruit the body's own immune cells to help tumors survive. Researchers say the findings, published in Biofabrication, reveal possible new targets to weaken the cancer's defenses and make

Researchers at the University of Pittsburgh, UPMC Hillman Cancer Center and the National Cancer Institute report that combining CAR T cell immunotherapy with a targeted radiopharmaceutical significantly improved tumor regression in preclinical models of neuroblastoma, a rare and

A new Northwestern Medicine study has discovered how radiotherapy alters the immune environment within cutaneous T-cell lymphoma (CTCL) tumors, according to findings published in the Journal of the American Academy of Dermatology.

For decades, cancer has been thought of as a purely human disease—rogue cells multiplying out of control, with no room for anything else in the picture. But a growing body of research suggests that isn't quite right. Some tumors, it turns out, come with company: communities of ba

A new therapy helps achieve a healthier BMI in people whose weight has become dysregulated following treatment for a brain tumor, a clinical trial has found. The results of the trial have been published in the New England Journal of Medicine. The new drug, setmelanotide, offers h

Scientists have identified a promising new strategy to tackle one of the biggest obstacles in treating glioblastoma, one of the most aggressive forms of brain cancer: resistance to chemotherapy. The study shows that an experimental compound called BA-101 can restore the effective