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Researchers discover a cause of neuron excitability in ALS, suggesting a new potential tre

Digging deep into the molecular mechanisms behind ALS, researchers at the Les Turner ALS Center at Northwestern Medicine have discovered why nerve cells overfire in the disease. Not only that—they have also designed a new drug to stop this overfiring, which could potentially slow

Admin Recifes 15/07/2026 1

Large multiple sclerosis brain cohort reveals biological differences linked to disease sev

Why does multiple sclerosis progress quickly in some people, while others remain stable for years? Researchers from the Netherlands Institute for Neuroscience have identified biological patterns in the brain that may help explain these differences. Their study shows that these pa

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Study reveals hidden distribution of noma disease in Nigeria

Noma, a deadly, rapidly progressing, noncontagious infection that destroys the soft tissues and bones of the mouth and face, remains one of the world's most neglected diseases. With a mortality rate of 80% to 90% if left untreated, the disease mainly affects young children living

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Alzheimer's biomarkers may forecast dementia progression in people 80 and older

Cognitive decline in very old adults has been considered for decades to be an almost inevitable consequence of aging. In clinical practice, this has contributed to many memory problems in patients over age 80 being interpreted as a natural part of aging, without further investiga

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Novel biomarker beats leading diagnostic blood test at predicting Alzheimer's progression

Small loops of genetic material may be strong indicators of imminent Alzheimer's disease (AD) symptoms. In a new study published in Nature Medicine, researchers showed that elevated levels of certain circular RNAs (circRNAs) in the blood nearly tripled patients' risk of developin

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Investigators report promising results from Phase II trial of targeted therapy for rare bi

Results of the ongoing eNRGy trial, a single-arm, multicenter, global Phase II clinical trial evaluating zenocutuzumab in solid tumors positive for Neuregulin 1 (NRG1) gene fusions, reported manageable side effects and clinically meaningful efficacy—including a near doubling of p

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Fatty liver drives a more dangerous form of colorectal cancer spread, study reveals

Researchers at VIB and KU Leuven, with international partners, have uncovered how fatty liver disease can fuel the most aggressive form of metastatic colorectal cancer. The findings, which appear in the journal Nature, not only explain why some patients face dramatically poorer o

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Tumors hijack macrophages after they clear dead cells, real-time tracking reveals

Researchers at Tel Aviv University's Gray Faculty of Medical and Health Sciences have uncovered how a natural and essential immune system process can be hijacked to promote cancer progression. In a new study, the research team developed an advanced technology that enabled it to t

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Parkinson's patients undergoing deep brain stimulation show little to no cortical Lewy pat

Researchers at the Icahn School of Medicine at Mount Sinai have found that patients with Parkinson's disease undergoing deep brain stimulation (DBS) show little to no Lewy pathology in the prefrontal cortex at the time of their DBS surgery, despite often having longstanding, clin

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EHA: Adding Pirtobrutinib to Venetoclax-Rituximab ups progression-free survival in chronic

For patients with relapsed/refractory (R/R) chronic lymphocytic leukemia (CLL), adding pirtobrutinib to venetoclax-rituximab (PVR) yields improved progression-free survival (PFS) compared to venetoclax-rituximab (VR), according to a study presented at the annual congress of the E

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Common brain cancer mutation changes DNA shape to drive progression, exposing therapeutic

A new study from researchers at The University of Texas MD Anderson Cancer Center has uncovered how one of the most common genetic alterations in glioma rewires the cancer cell genome to fuel tumor progression, suggesting a potential new therapeutic strategy for patients with ATR

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Genetic information helps predict the onset and progression of glaucoma

Glaucoma is the leading cause of irreversible visual impairment worldwide. Because the disease often progresses without symptoms for years, many patients are diagnosed only after permanent damage to the optic nerve has already occurred. Earlier detection through targeted screenin

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