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170 notícias encontradas para "rare"
A blood protein can flag dementia risk decades before symptoms appear
A blood protein can flag dementia risk decades before symptoms appear
Forgetting the name of a loved one may be one of the first signs people notice of dementia, but it's rarely the first warning sign your brain gives. Changes in the brain that lead to neurodegenerative diseases like Alzheimer's and dementia start showing up decades before symptoms
Improving growth outcomes for children living with dwarfism
New findings from a trial conducted at Children's Hospital Colorado (Children's Colorado) and University of Colorado (CU) Anschutz School of Medicine demonstrate significantly increased growth rates in children with achondroplasia, the most common form of dwarfism. These results
CAR T cell therapy targets key mutation driving rare blood cancers
CAR T cell therapy targets key mutation driving rare blood cancers
A new form of CAR T-cell therapy has been designed to find and destroy the cancer-driving stem cells responsible for a group of blood cancers known as myeloproliferative neoplasms (MPNs), while leaving healthy blood cells unharmed, according to new research led by UCL and Univers
Investigators report promising results from Phase II trial of targeted therapy for rare bi
Results of the ongoing eNRGy trial, a single-arm, multicenter, global Phase II clinical trial evaluating zenocutuzumab in solid tumors positive for Neuregulin 1 (NRG1) gene fusions, reported manageable side effects and clinically meaningful efficacy—including a near doubling of p
Going from the lab into the fire to study cancer risk in wildland firefighters
Going from the lab into the fire to study cancer risk in wildland firefighters
Cancer researchers at the Sylvester Firefighter Cancer Initiative (SFCI), part of the University of Miami Miller School of Medicine, took a rare step to better understand the cancer risks wildland firefighters face: They became wildland firefighters themselves. The firsthand expe
Foto: Marek Piwnicki / Pexels
Virus influences rare brain lymphomas, large study finds
Primary CNS lymphoma is a rare cancer that arises from malignant white blood cells. Affected individuals develop tumors in the brain and, more rarely, in the spinal cord, the eyes or within the cerebrospinal fluid. These lymphomas can occur in people with weakened immune systems,
Repurposed cancer drug rapidly eased rare autoimmune neuropathy in two patients
An interdisciplinary team at Jena University Hospital achieved a surprisingly rapid and significant improvement in two patients with an autoimmune peripheral nervous system disorder. The team administered teclistamab, a drug originally developed for multiple myeloma, and reported
Foto: Kindel Media / Pexels
AI tool can identify biological profiles associated with thrombosis risk
Two people may be the same age and have similar family histories or risk factors, yet only one of them may develop thrombosis. To better understand why this occurs, researchers from the Complex Disease Genomics Unit at the Sant Pau Research Institute (IR Sant Pau) and the Biomedi
A rare, Ebola-like virus is spreading. Are we prepared?
A rare, Ebola-like virus is spreading. Are we prepared?
A growing outbreak of the rare Bundibugyo virus in the Democratic Republic of Congo highlights the need for better planning against lesser-known but potentially deadly infectious diseases, according to a review article by Boston University professor Nancy Sullivan, published June
New approach could expand CAR T therapy from blood cancers to solid tumors
New approach could expand CAR T therapy from blood cancers to solid tumors
Researchers at the University of Pittsburgh, UPMC Hillman Cancer Center and the National Cancer Institute report that combining CAR T cell immunotherapy with a targeted radiopharmaceutical significantly improved tumor regression in preclinical models of neuroblastoma, a rare and
Promising medication combination to treat an 'undruggable' type of lung cancer
Breakthrough research led by scientists in Manchester has identified a new drug combination that could improve outcomes for thousands of patients with lung cancer driven by a rare type of KRAS mutation, offering hope for patients worldwide with this difficult-to-treat subtype of
Radiotherapy reprograms immune response in rare skin cancer
A new Northwestern Medicine study has discovered how radiotherapy alters the immune environment within cutaneous T-cell lymphoma (CTCL) tumors, according to findings published in the Journal of the American Academy of Dermatology.