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Data highlight progress toward personalized stem cell therapy for Parkinson's disease
Interim clinical findings from the first Phase I/IIa trial using autologous-induced pluripotent stem cell (iPSC)-derived dopamine neuron precursor cells, along with the novel quality-control tools developed to manufacture these individualized therapies, have been presented by Jea
Huntington's treatment quest reaches first pluripotent stem cell trial, with safety now un
An update on the first clinical trial evaluating a pluripotent stem cell-derived neural stem cell therapy for Huntington's disease was presented at the ISSCR 2026 Annual Meeting. The Phase Ib/IIa REGEN4HD study represents a significant translational milestone following years of p
FDA expands use of first sickle cell disease gene therapy for children as young as 2 years
The U.S. Food and Drug Administration has issued a supplemental approval for Casgevy (exagamglogene autotemcel) for patients ages 2 and older with either sickle cell disease (SCD) with recurrent vaso-occlusive crises (VOCs) or transfusion-dependent β thalassemia (TDT). Supplement
As the US recovers from its latest heat wave, study warns of an increase in hospitalizatio
As the U.S. recovers from its July 4 heat wave, a new study in Nature Health warns of an impending uptick in people attending hospitals for mental health and behavioral disorders, according to the first multicountry study of heat wave-related mental health hospitalization, led by
First-in-human immunotherapy more than doubles progression-free survival in glioblastoma p
First-in-human immunotherapy more than doubles progression-free survival in glioblastoma p
Glioblastoma, the most aggressive malignant brain tumor in adults, remains one of the most challenging cancers to treat because of limited treatment options and a poor prognosis. Patient outcomes have remained largely unchanged in the past two decades, underscoring the need for i
New first-in-human study explores immune-engineered cell therapy approach for type 1 diabe
New first-in-human study explores immune-engineered cell therapy approach for type 1 diabe
New research presented at the International Society for Stem Cell Research (ISSCR) 2026 Annual Meeting explores an approach that could expand the potential of cell replacement therapy for type 1 diabetes by evaluating whether immune-engineered, allogeneic insulin-producing cells
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Second prostate-specific membrane antigen PET scan can change treatment for nearly half of
A second prostate-specific membrane antigen (PSMA) PET scan changed treatment plans for nearly half of patients whose first scan was negative, according to new research published in the July issue of The Journal of Nuclear Medicine. Findings from the repeat PSMA scans, which incl
New study provides first evidence of dopamine system injury in the brain of long COVID pat
New study provides first evidence of dopamine system injury in the brain of long COVID pat
A new brain imaging study led by researchers at the Center for Addiction and Mental Health (CAMH), published in eBioMedicine, provides the strongest evidence to date that long COVID is associated with injury to dopamine-releasing neurons in the brain—a finding that may explain sy
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Social media likes may have a bigger influence on people with depression
One of the first things many people do after posting on social media is check how many likes they have and who has liked their content. This habit can be an instant mood booster when a post is popular.
Researchers reveal immune mechanisms that drive development of rare allergic stomach disea
Researchers reveal immune mechanisms that drive development of rare allergic stomach disea
Researchers at Tel Aviv University have developed one of the first experimental models that faithfully reproduces eosinophilic gastritis (EoG), a rare but increasingly recognized allergic disease of the stomach. Using this model, they identified the immune pathways responsible fo
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Cannabis-derived treatment eases agitation in hospice-eligible dementia patients, trial fi
In a first-of-its-kind clinical trial, U.S. researchers found that people with agitation and dementia in late life who took a special medical formulation of two active ingredients found in marijuana—THC and CBD—had significantly less agitation than people who received a placebo.
First diagnostic X-rays in space mark new era for astronaut health
First diagnostic X-rays in space mark new era for astronaut health
A team of crew members aboard a commercial spaceflight acquired the first diagnostic X-rays during an orbital flight. Results of the mission were published today in Radiology.