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After amyloid plaques form, tau and alpha-synuclein pathology rises in mice
After amyloid plaques form, tau and alpha-synuclein pathology rises in mice
The aging brain frequently harbors multiple protein pathologies that contribute to Alzheimer's, Parkinson's and other neurodegenerative diseases. But how do these problematic proteins interact with each other, and could these interactions inform future therapies? Researchers at T
Kidney disease profile shifts: Diabetes-linked CKD rises as overall US rate stalls
Chronic kidney disease (CKD) is common, largely silent and serious. Most people who have the condition do not realize they have it, while it sharply raises the risk of heart attacks, strokes, kidney failure and early death. Over the past decade, the share of American adults livin
Portable PS-OCT scanner could reveal donor liver health without biopsy
Each year, thousands of patients in the United States wait for a liver transplant, while transplant teams must make rapid, difficult decisions about whether donor organs are suitable for use. Many of those livers, particularly from older or medically complex donors, require caref
Chlorhexidine blend wipes out 99.9% of Candida parapsilosis cells in lab tests
A 0.5% alcohol-based chlorhexidine antiseptic, combined with the natural organic compounds eugenol and menthol, can eliminate 99.9% of Candida parapsilosis cells. This fungus is one of the leading causes of infections in hospital settings, such as intensive care units (ICUs).
In São Paulo, Brazil, the expansion of bike lanes and parks encourages residents to cycle
According to a study that analyzed the behavior of 1,500 São Paulo residents between 2014 and 2024, the implementation of new bike lanes, parks and other public facilities in the Brazilian city has encouraged transportation-related physical activity and promoted public health ben
One-size-fits-all fetal growth charts often fail to spot at-risk babies, large study finds
One-size-fits-all fetal growth charts used in the NHS to monitor babies' growth before birth often misclassify babies as being either too small or too large, which can lead to missed cases at risk of stillbirth or unnecessary interventions, finds a study of more than 3 million NH
Most obesity drugs do not improve quality of life or heart health, analysis indicates
Most obesity drugs do not improve quality of life or heart health, analysis indicates
Despite substantial weight loss, most obesity drugs such as Wegovy and Mounjaro do not meaningfully improve quality of life, and few show cardiovascular benefits at one year, according to an analysis of the latest evidence published by The BMJ.
Commonly used drugs show small benefit for long COVID fatigue
Over-the-counter antihistamines and a prescription anti-inflammatory drug both have a small benefit in reducing long COVID fatigue among people receiving care from specialist long COVID clinics, according to new findings from a large clinical trial led by UCL and UCLH.
Cellular 'bandages' help rebuild uterine lining after monthly shedding, study finds
For most women past puberty, the uterine lining (endometrium) sheds from the body roughly every month if there is no fertilized egg present. Then, the uterus rebuilds itself to prepare for a potential pregnancy. While this process—the menstrual cycle—is widely known, how it works
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Sleep problems in dementia care are linked more to emotional well-being than fear of falli
While fear of falling has long been linked to poor sleep among older adults, new research from George Mason University suggests that emotional well-being may be an even stronger predictor of sleep quality for people with dementia and the spouses who care for them. In what is beli
Alcohol drives opposite brain circuit changes in amyloid and tau Alzheimer's models
Alcohol use has been associated with an increased risk of cognitive decline and dementia. But new research from Texas A&M University's Naresh K. Vashisht College of Medicine at Texas A&M Health suggests the relationship between alcohol and Alzheimer's disease is more complicated
Moderate, home-based exercise found safe for aortic dissection survivors
Moderate, home-based exercise found safe for aortic dissection survivors
A multicenter clinical trial led by UTHealth Houston has found that survivors of aortic dissection can participate in moderate-intensity exercise at home without increasing the risk of recurrent aortic events. The study is published in Circulation: Population Health and Outcomes.