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Gene discovery may unlock infertility, early menopause clues
Most women are aware that fertility declines dramatically with age. This is mainly due to the gradual loss of eggs and follicles from the ovaries, leading to infertility, irregular cycles and ultimately menopause.
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Body's own cell-to-cell messaging packets studied as the basis for next-generation medicin
The Blood and Tissue Bank is studying how to therapeutically manufacture and use a type of nanoparticles released by the body's cells to communicate with one another, in one of the most promising fields of research for the therapies of the future. New medicines and advanced thera
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Signaling pathway may help predict immunotherapy response in glioblastoma
Northwestern Medicine scientists have uncovered a biological mechanism that helps explain why most patients with glioblastoma fail to respond to immunotherapy, according to their study published in Nature Communications.
Dialing back stiffness may protect muscles in myotonic dystrophy
For decades, researchers studying myotonic dystrophy type 1 (DM1) have focused on the disease's underlying genetic cause: a mutation that produces a toxic form of RNA, disrupting the normal processing of thousands of genetic messages inside cells. While scientists have known this
New poll reveals who is most likely to endorse vaccine myths
People who don't have a trusted health care provider are more likely than people with one to believe or lean toward believing several common myths about vaccines, a new KFF Tracking Poll on Health Information and Trust reveals.
A natural compound steps into the estrogen arena
Uterine fibroids and endometriosis are two of the most common gynecologic diseases, affecting 15% to 80% of women of childbearing age. Existing treatments—hormonal drugs and selective estrogen receptor modulators—have side effects and cannot reliably prevent recurrence. This is w
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Chronic consumption of xanthan gum may cause inflammation in the colon
Xanthan gum is found almost everywhere. This food additive has thickening, stabilizing and gelling properties and is one of the food industry's most widely used additives for adjusting the consistency of ice cream, yogurt, cakes, sauces and gluten-free pasta. It is also used to p
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Rapid magnetic brain stimulation eases depression within days, but benefits fade within we
Despite decades of advances in mental health care, depression remains one of the world's most disabling conditions. Many people with major depressive disorder (MDD) fail to find lasting relief from antidepressants or psychological therapies. Studies indicate that the global burde
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Student-led study aims to improve diagnosis of early-onset dementia, a frequently misdiagn
Research led by a University of Sydney medical student could enable earlier and more accurate diagnosis of behavioral variant frontotemporal dementia—one of the most commonly misdiagnosed forms of early-onset dementia, which can begin as early as a person's late 40s and is often
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Two-isotope imaging could guide targeted alpha therapy for metastatic prostate cancer
Prostate cancer is one of the most common cancers affecting men worldwide. However, planning personalized radiotherapy in the advanced stages of the disease still requires more precise tools. Researchers at the Helmholtz-Zentrum Dresden-Rossendorf (HZDR) have now tested a novel a
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Immunotherapy shows long-term promise in aggressive lymphoma
A leading-edge immunotherapy may extend survival for patients with one of the most aggressive forms of blood cancer, according to newly published five-year results from a major clinical trial in the Blood Journal. The clinical trial evaluated lisocabtagene maraleucel (liso-cel),
One in four adults has metabolic syndrome, and it may be aging their brains
One in four adults has metabolic syndrome, and it may be aging their brains
An estimated 1 in 4 adults worldwide has metabolic syndrome. While metabolic syndrome is most often thought of as a warning sign that diabetes or cardiovascular disease may be on the horizon, my team's new study suggests that its consequences reach further—and it may actually be