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330 notícias encontradas para "direct"
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Armed conflict is linked to increased measles cases globally
Countries experiencing armed conflict tend to report more measles cases, and the elevated risk persists even a year after the fighting, according to new research published in PLOS Medicine. The study links armed conflict to measles in two ways: directly, by disrupting immunizatio
Intravesical CAR T therapy opens door to bladder-sparing cancer treatment
Researchers at Weill Cornell Medicine, Cedars-Sinai Medical Center and Roswell Park Comprehensive Cancer Center have developed genetically engineered CAR T cells that specifically target and kill bladder cancer cells. The study, published in the Journal of Experimental Medicine (
Neural pathways reveal a push-pull system for coordinating goal-directed behavior in mice
Most of the tasks that humans complete daily entail carefully coordinating movements and tracking progress made toward a desired goal. Past studies have highlighted the role of the basal ganglia (BG), a set of interconnected structures deep within the brain, in the selection, con
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Fatty liver drives a more dangerous form of colorectal cancer spread, study reveals
Researchers at VIB and KU Leuven, with international partners, have uncovered how fatty liver disease can fuel the most aggressive form of metastatic colorectal cancer. The findings, which appear in the journal Nature, not only explain why some patients face dramatically poorer o
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Digital badge program helps developers improve mental health apps
In "Evaluating the Evidence Base for New Mental Health Tech With APA Labs," JMIR correspondent Simon Spichak speaks with Tanya Carlson, MBA, managing director of APA (American Psychological Association) Labs, on how a new initiative—the Digital Badge Program—is helping developers
The ethics of being left out of health research
Beyond its importance for scientific discovery, representation in health research directly influences health care planning, policy development and resource allocation.
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Gut bacteria boost immune system, help send vitamin A to T cells
Scientists at UT Southwestern Medical Center have discovered that gut bacteria help regulate the development of the body's immune system by directing the movement of vitamin A through a previously unrecognized cellular network. The preclinical findings, published in Cell Host & M
Liver-directed gene therapy shows preclinical efficacy for severe inherited metabolic diso
Genespire, in collaboration with researchers at the San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), announced the publication of preclinical data supporting the potential of its liver-directed immune-shielded lentiviral gene therapy approach to treat methylmalonic ac
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Ureters stay visible for hours with dye designed to vanish through kidneys
A cross-disciplinary research team led by Hongjie Dai, director of the Materials Institute of Life Sciences and Energy (MILES) at the University of Hong Kong (HKU) in Shenzhen, has developed a promising near-infrared (NIR) fluorescent dye for potential clinical use in ureter imag
Secondhand smoke independently disrupts children's sleep
A new study from Ben-Gurion University of the Negev (BGU) has found that children exposed to secondhand smoke have significantly poorer sleep quality and greater sleep fragmentation, independent of the severity of their breathing problems. The prospective clinical trial, publishe
Ibuprofen safely dampens inflammatory markers in 28-patient drug-resistant tuberculosis tr
The Experimental Tuberculosis Unit (UTE) at the Germans Trias i Pujol Research Institute (IGTP) has published in Nature Communications the results of a phase IIa pilot clinical trial assessing ibuprofen as a host-directed therapy in patients with pre-extensively drug-resistant tu
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A new option for long-term care costs
An estimated 70% of Americans will need long-term care at some point in their lives, but "they haven't planned for it or saved for it," said Cathleen MacCaul, advocacy director for AARP Washington State, which supported the legislation that created WA Cares.