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191 notícias encontradas para "drug"
Dementia-causing substance turns into a therapeutic 'switch' with new Alzheimer's drug str
A substance that worsens dementia has become a "switch" that initiates treatment. KAIST researchers have developed a new therapeutic approach that uses hydrogen peroxide (H₂O₂), a reactive oxygen species that damages cells and increases in the brains of patients with Alzheimer's
Alcohol is one of the most dangerous drugs, yet its presence is ubiquitous in social setti
Few substances are as deeply woven into everyday life as alcohol. It is a fixture at holiday celebrations, work-related social gatherings, sporting events, airports and brunch or dinner tables. A raised glass for a toast, the ubiquitous wedding open bar or drinks shared during a
'Polypill' for heart failure cuts hospitalizations and ER visits by 60% in trial
A "polypill" combining three medications recommended to treat heart failure into a single daily dose proved far more effective for patients than taking the drugs separately, a randomized clinical trial led by UT Southwestern Medical Center researchers showed. The findings, publis
FDA lets 20 ZYN nicotine pouches claim lower risk than cigarettes; critics warn of danger
The U.S. Food and Drug Administration (FDA) has authorized marketing of 20 ZYN nicotine pouch products as a lower-risk option than cigarettes, a decision that drew immediate criticism from anti-cancer advocates worried about youth use.
Biomarker-matched drug combos shrink treatment-resistant melanoma in preclinical models
A new study led by researchers at The University of Texas MD Anderson Cancer Center has identified a way to tailor drug combinations based on specific tumor biology to improve outcomes for treatment-resistant advanced melanoma.
New drug unlocks elusive immune receptor, opening path toward motor neuron disease treatme
University of Queensland researchers have developed a drug that activates a hard-to-target immune receptor—a breakthrough that could lead to new treatments for neurodegenerative conditions like motor neuron disease (MND).
FDA approves Tzield for children with new stage 3 type 1 diabetes
The U.S. Food and Drug Administration has granted accelerated approval to Sanofi's Tzield (teplizumab-mzwv) to delay the decline in endogenous insulin production in children aged 8 to 17 years recently diagnosed with stage 3 type 1 diabetes.
AI tool improves prediction of who will respond to cancer immunotherapy drugs
Cancer immunotherapy drugs known as immune checkpoint inhibitors (ICIs) can be miracle drugs for cancer patients, curing some and turning deadly disease into a manageable chronic condition in others. But these drugs work for only a subset of patients, with few indications why—a k
The workers who 'just get it': How lived experience strengthens addiction recovery
People with lived experience of alcohol and drug use are helping others navigate recovery. New UNSW research shows their experience is a powerful form of expertise when workplaces recognize and support it. The research is published in the International Journal of Drug Policy.
Repurposed cancer drug rapidly eased rare autoimmune neuropathy in two patients
An interdisciplinary team at Jena University Hospital achieved a surprisingly rapid and significant improvement in two patients with an autoimmune peripheral nervous system disorder. The team administered teclistamab, a drug originally developed for multiple myeloma, and reported
Researchers uncover possible cause of muscle pain from widely used cholesterol medication
Researchers uncover possible cause of muscle pain from widely used cholesterol medication
Millions of people rely on statins, a medication used to lower cholesterol and reduce the risk of heart attack and stroke. But for some, the drugs come with an unwelcome trade-off: muscle pain, weakness and exercise intolerance that can make it difficult to continue treatment. No
Fibronectin pathway may drive Marfan aortic damage, opening new drug targets
A new study published in Nature Communications identifies a molecular signaling pathway that contributes to the development of life-threatening aortic aneurysms and dissections in Marfan syndrome, a genetic disorder affecting connective tissue. The findings provide new insight in