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Chromatin hubs help decide whether T cells fight chronic threats or fail
Chronic and viral infections can literally exhaust certain key cells in the immune system from a constant barrage of attacks. But a new pair of papers by scientists at the Hackensack Meridian Center for Discovery and Innovation (CDI) points to a way to understand how this exhaust
Untangling the risk factors for developing multiple chronic conditions among UK South Asia
In a study published in PLOS Medicine, Daniel Stow, Ph.D., an epidemiologist at Queen Mary University of London, UK, and collaborators discovered factors that increase the risk of developing several long-term, coexisting health conditions among South Asian populations in the Unit
Glycoprotein G unlocks genital herpes spread to nerves, revealing vaccine target
Researchers at the University of Gothenburg have identified a key protein that allows the virus that causes genital herpes to get into the nervous system. The discovery, made in experiments on mice, could pave the way for future vaccines against the disease. The study is publishe
Researchers discover new form of hereditary prostate cancer
Researchers discover new form of hereditary prostate cancer
Researchers at the University of British Columbia have identified a new form of hereditary prostate cancer that, while rare, can cause aggressive disease at a young age. The discovery paves the way for genetic testing programs that could help identify at-risk families and support
Genome editing in rats enables more accurate estrogen receptor-positive breast cancer mode
Rat disease models have played an integral role in scientific discovery and cancer research, including Nobel Prize–winning work from Charles Huggins on hormone therapy for prostate cancer in 1966. However, technical challenges in genetic engineering of rat models have limited the
Damaged myelin generates abnormal rhythms in the sleeping brain
Scientists have discovered how damage to the myelin sheath—the insulating layer around nerve fibers—affects brain activity during sleep.
Foto: Tara Winstead / Pexels
Genetic mapping identifies new hope for bone diseases
In a global breakthrough published in Nature Genetics, researchers have successfully mapped the cells and genes that regulate bone formation and loss at an unprecedented scale and discovered the critical role that blood vessel cells play in bone health.
How AI accelerates radiopharmaceutical drug discovery, optimizes personalized dosimetry
A feature News and Perspectives story on technological advances in oncology was published in Journal of Medical Internet Research. Authored by JMIR Correspondent Benedette Cuffari, "AI-Designed Radiopharmaceuticals: How Machine Learning Is Redefining Precision Cancer Therapy" rep
Night owls eat later, choose less nutritious food, carry more belly fat and show higher me
For generations, early to bed and early to rise was seen as the blueprint for a healthy life, and any departure from it was often considered unhealthy. Scientists, however, have discovered that whether someone is an early bird who wakes up early and starts the day with energy or
Gene discovery may unlock infertility, early menopause clues
Most women are aware that fertility declines dramatically with age. This is mainly due to the gradual loss of eggs and follicles from the ovaries, leading to infertility, irregular cycles and ultimately menopause.
Cellular recycling protein plays critical protective role in the gut
Australian researchers have discovered that even a modest reduction in the protein BECLIN1 leads to a significant increase in gut inflammation, which can lead to further disease and complications over time.
Epigenetic therapy shows promise against treatment-resistant AML
Researchers at The University of Texas MD Anderson Cancer Center have discovered that an investigational epigenetic therapy remained effective in treatment-resistant acute myeloid leukemia (AML) by activating the Hippo pathway, a tumor-suppressing pathway linked to cancer growth