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483 notícias encontradas para "published"
CAR T cell therapy leads to 10-year remissions in B-cell lymphoma patients
CAR T cell therapy leads to 10-year remissions in B-cell lymphoma patients
After a median follow-up of 10 years, more than one-third of patients with large B-cell lymphoma and nearly half of patients with follicular lymphoma who received a single infusion of tisagenlecleucel—the CAR T-cell therapy developed by Carl June, MD, that would go on to become t
Targeting cannabinoid receptors in bladder sensory pathways may alleviate pain of cystitis
The burning pain associated with cystitis affects millions of people around the world, and it can take days or even years for some patients to find relief from bladder pain, infection-related symptoms and the constant need to urinate. A new study led by Flinders University publis
Foto: Merlin Lightpainting / Pexels
AI framework helps identify new targets for CAR T cell therapy
Leading CAR T cell therapy researchers have developed a human-in-the-loop artificial intelligence (AI) framework that centers scientists' expertise to find viable target antigens for CAR T cell therapy. The work was led by experts from the Perelman School of Medicine at the Unive
Foto: Marta Branco / Pexels
Molecular machinery in cardiac mitochondria reacts to metabolic stress in unexpected way
In a recent study published in Nature Communications, researchers at Karolinska Institutet report that the molecular machinery responsible for cellular energy conversion is more interconnected than previously understood, shedding light on how mitochondria adapt under stress.
Foto: lalesh aldarwish / Pexels
Negative link seen between illness perception, self-management behavior in inflammatory bo
For patients with inflammatory bowel disease (IBD), there is a significant negative correlation between illness perception and self-management behavior, according to a study published online June 16 in Scientific Reports.
Special protein in the brain's cleansing system may contribute to loss of brain function i
Alzheimer's disease is a progressive and permanent loss of nerve cells in the brain. The breakdown causes memory loss, functional impairment and personality changes. In a new study published in Nature Aging, researchers found that the age-related reduction in a specific protein m
Foto: Emir Bozkurt / Pexels
Armed conflict is linked to increased measles cases globally
Countries experiencing armed conflict tend to report more measles cases, and the elevated risk persists even a year after the fighting, according to new research published in PLOS Medicine. The study links armed conflict to measles in two ways: directly, by disrupting immunizatio
Foto: Anna Tarazevich / Pexels
Significant association identified between hepatitis C, overactive bladder
There is a significant association between hepatitis C virus (HCV) and overactive bladder (OAB), according to a study published online May 29 in BMC Urology.
Smartphone-based self-screening can identify ocular surface malignancies
Integration of smartphone-based imaging and artificial intelligence (AI)-driven diagnostics provides an effective strategy for screening for rare ocular malignancies, according to a study published online June 4 in JAMA Ophthalmology.
Foto: Leon Aschemann / Pexels
Patients with lupus have increased risk of chronic kidney disease, mortality
Patients with systemic lupus erythematosus (SLE) without lupus nephritis (LN) have increased risk of chronic kidney disease (CKD) and mortality, according to a study published June 16 in Rheumatology.
First potential probiotic treatment for lupus identified by researchers
First potential probiotic treatment for lupus identified by researchers
Scientists at UT Health San Antonio, the academic health center of The University of Texas at San Antonio, have found a link between a bacterium in the gut microbiome (ecosystem) and lupus that could lead to more effective treatment of the disease, described in a study published
Identifying immune pathways driving aggressive brain cancers
A new study has uncovered a key mechanism that helps one of the deadliest brain cancers evade the immune system, according to the study published in The Journal of Clinical Investigation.