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635 notícias encontradas para "researchers"
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Developing a new methodology to identify biomarkers for male infertility
Researchers from the EHU-University of the Basque Country have developed a robust protocol to detect the molecules involved in the metabolic reactions of sperm. The new method enables a detailed analysis even with small samples and allows the detection of the largest number of po
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AI framework helps identify new targets for CAR T cell therapy
Leading CAR T cell therapy researchers have developed a human-in-the-loop artificial intelligence (AI) framework that centers scientists' expertise to find viable target antigens for CAR T cell therapy. The work was led by experts from the Perelman School of Medicine at the Unive
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Language models read doctors' notes to reveal why patients discontinue medication
Researchers at the University of Tartu showed that large language models can identify with high accuracy why patients stop using antidiabetic medications or statins based on doctors' electronic clinical notes. The study opens new possibilities for using clinical information that
Hidden thymus step may prime cancer-killing T cells earlier than expected
Hidden thymus step may prime cancer-killing T cells earlier than expected
Researchers at Mayo Clinic have uncovered a previously hidden step in how the immune system prepares to fight cancer, a discovery that could help scientists develop more effective and longer-lasting cancer immunotherapies.
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Molecular machinery in cardiac mitochondria reacts to metabolic stress in unexpected way
In a recent study published in Nature Communications, researchers at Karolinska Institutet report that the molecular machinery responsible for cellular energy conversion is more interconnected than previously understood, shedding light on how mitochondria adapt under stress.
Special protein in the brain's cleansing system may contribute to loss of brain function i
Alzheimer's disease is a progressive and permanent loss of nerve cells in the brain. The breakdown causes memory loss, functional impairment and personality changes. In a new study published in Nature Aging, researchers found that the age-related reduction in a specific protein m
New Tfr cell model uncovers molecular switches that restrain antibody responses
New Tfr cell model uncovers molecular switches that restrain antibody responses
For the immune system to effectively combat pathogens, antibody responses must be precisely controlled. So-called follicular regulatory T cells (Tfr cells) play a key role in this process by limiting excessive immune responses and helping to maintain immune tolerance. Researchers
Opposing protein pathways steer skin stem cells toward renewal or repair
Two proteins with opposing functions orchestrate the development and maintenance of healthy skin, Stanford Medicine researchers have found. Modulating their activity with topical drugs could reduce inflammation, aid wound healing and slow or halt the growth of skin cancer, the re
Leveraging AI can reduce time and resources in how physicians approach sepsis care
In a new clinical study from the University of California San Diego School of Medicine, researchers and physicians at UC San Diego Health have found that by utilizing artificial intelligence (AI), they could develop more timely and efficient assessments of care provided to patien
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Nanotech platform combining paclitaxel with siRNA boosts immune response against lung canc
Researchers at the University of Arizona R. Ken Coit College of Pharmacy have developed a new strategy that helps the immune system recognize and attack lung cancer tumors more effectively. By packaging a chemotherapy drug and an RNA molecule in a tiny lipid carrier, the team boo
First potential probiotic treatment for lupus identified by researchers
First potential probiotic treatment for lupus identified by researchers
Scientists at UT Health San Antonio, the academic health center of The University of Texas at San Antonio, have found a link between a bacterium in the gut microbiome (ecosystem) and lupus that could lead to more effective treatment of the disease, described in a study published
Those most at risk from heat have the least access to air conditioning, UK study finds
People who are most in danger during the U.K.'s heat wave are among the least likely to have air conditioning at home, researchers have found. With temperatures potentially rising to 40° C (104° F), scientists at the University of Reading have looked at how many homes in England