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260 notícias encontradas para "used"
AI-guided CRISPR uncovers oxytocin receptor as unexpected psoriasis drug target
Biohub researchers have performed what they believe is the first genome-wide CRISPR study of primary human adult skin cells, then used an AI model to mine the results for overlooked drug targets for psoriasis. They found an unlikely candidate: the receptor for oxytocin, a hormone
One-size-fits-all fetal growth charts often fail to spot at-risk babies, large study finds
One-size-fits-all fetal growth charts used in the NHS to monitor babies' growth before birth often misclassify babies as being either too small or too large, which can lead to missed cases at risk of stillbirth or unnecessary interventions, finds a study of more than 3 million NH
Commonly used drugs show small benefit for long COVID fatigue
Over-the-counter antihistamines and a prescription anti-inflammatory drug both have a small benefit in reducing long COVID fatigue among people receiving care from specialist long COVID clinics, according to new findings from a large clinical trial led by UCL and UCLH.
Simple assessment tools are accurate in predicting older adults' health
Simple assessment tools are accurate in predicting older adults' health
Several tools are currently used to assess the health of older people and their risk of future health problems, but it is unclear which perform best. A new study published in BMC Medicine compares seven widely used geriatric assessment tools. The results show that a relatively si
Genome editing in rats enables more accurate estrogen receptor-positive breast cancer mode
Rat disease models have played an integral role in scientific discovery and cancer research, including Nobel Prize–winning work from Charles Huggins on hormone therapy for prostate cancer in 1966. However, technical challenges in genetic engineering of rat models have limited the
Unmedicated women with depression do not tolerate heat as well as those on SSRIs
Media stories, social media posts and the U.S. Centers for Disease Control and Prevention have asserted that selective serotonin reuptake inhibitors (SSRIs)—a class of medication commonly used to treat mental health conditions including depression and anxiety—may increase people'
Eye movements reveal personal 'fingerprints' as people explore unfamiliar scenes
Walk into a crowded coffee shop, and what catches your eye as you take in the scene could say as much about you as the spirals on your fingertips or the mutations in your DNA. Eye movements are so unique, in fact, that they could be used to identify you through objects that have
Economic evaluation supports prophylactic naldemedine for opioid-induced constipation in c
Economic evaluation supports prophylactic naldemedine for opioid-induced constipation in c
Although opioids remain indispensable for pain relief in patients with advanced cancer, their use frequently results in OIC, which can substantially reduce quality of life and, in some cases, compromise the continuation of optimal pain management. Naldemedine, a peripherally acti
Engineers develop AI tool to design peptides that turn signals on or off
To develop new and better peptides, the short amino acid strings behind medicines like GLP-1 drugs, researchers have used AI to generate candidates and to predict their properties.
Scientists improve the analgesic efficacy of morphine
Scientists improve the analgesic efficacy of morphine
Scientists at the Department of Cell Biology of the University of Malaga have taken a step forward in the search for more effective treatments for pain with a new study that advances efforts to mitigate the addictive effects of morphine—one of the main drugs used for this purpose
Foto: Google DeepMind / Pexels
Demystifying the molecular mechanisms of general anesthesia
Researchers at Weill Cornell Medicine and Birkbeck, University of London, have identified a site where a commonly used anesthetic binds to sodium ion channels, revealing a molecular mechanism that may explain how these drugs dampen communication between neurons. Ion channels are
Advanced climate models used to estimate temperature-related suicide patterns by 2050
A large international team, including researchers from the University of Tokyo, wanted to know whether and how climate change might increase the number of temperature-related suicides around the world. Previous studies have shown that hotter weather is often linked to a higher ri