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A novel oral vaccine platform using genetically engineered Bifidobacterium could enhance anti-tumor immunity. In an exploratory Phase I clinical study, the vaccine was well tolerated and generated immunologic and clinical findings that warrant further investigation. The results a

A leading-edge immunotherapy may extend survival for patients with one of the most aggressive forms of blood cancer, according to newly published five-year results from a major clinical trial in the Blood Journal. The clinical trial evaluated lisocabtagene maraleucel (liso-cel),

The first clinical trial of an antiviral drug's effectiveness in people exposed to the deadly Ebola strain spreading in the Democratic Republic of Congo is underway, the WHO said Tuesday.

Among adults with insulin-treated diabetes, initiation of continuous glucose monitoring (CGM) by primary care clinicians is associated with clinically meaningful improvements in hemoglobin A1c (HbA1c) and significant reductions in recurrent hospitalizations, according to a study

A new study shows that a smoking cessation treatment program delivered in community oncology care settings can nearly double quit rates for patients with cancer who currently smoke. Investigators from Mass General Brigham Cancer Institute and Memorial Sloan Kettering Cancer Cente

Two optimistic drinkers bumble around with a lovelorn student in tow in a depressing yet funny, faintly baffling tragicomedyFrancesco Sossai’s new film is not one that recognises the spoilsport clinical concept of “alcoholism”. Rather, it is the cynically amused and lenient witne

Egg cells missing a key protein may be more likely to end up with the wrong number of chromosomes, but an mRNA injection that helps the cells make the protein reduces the problem

Report uncovers biggest childbirth scandal in NHS history in which 520 mothers and babies suffered ‘potentially avoidable’ harm or diedHorrific failings led to 520 mothers and babies in Nottingham suffering harm or dying, sparking calls for a public inquiry into maternity care ac

Canada’s home World Cup is over. Jesse Marsch and his men are now a road team, despite the spectacular efforts of the substitute Promise David.A 12-minute burst of clinical finishing early in the second half, after a dogfight of a first, earned Switzerland the right to call Vanco

Saracens 52-14 TrailfindersEight tries for winners in front of 8,000 fansSaracens just needed three ingredients to play Trailfinders off the pitch and win their first Premiership Women’s Rugby title in four years: clinical attack, brick-wall defence and an immense kicking game. N

Captain Hayley Matthews says pressure off in semi-finalSix-time champions Australia unbeaten in tournamentHayley Matthews says her West Indies team are leaning into their status as massive underdogs when they play Australia in the first T20 World Cup semi-final at the Oval on Tue

Noskova reaches her first major finalCzech wins 6-4, 6-4 with clinical displayLinda Noskova had arrived at Wimbledon as one of the most dangerous young talents yet to make a grand slam breakthrough but the Czech completed that journey on Thursday, producing a clinical display to