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199 notícias encontradas para "drug"
How AI accelerates radiopharmaceutical drug discovery, optimizes personalized dosimetry
A feature News and Perspectives story on technological advances in oncology was published in Journal of Medical Internet Research. Authored by JMIR Correspondent Benedette Cuffari, "AI-Designed Radiopharmaceuticals: How Machine Learning Is Redefining Precision Cancer Therapy" rep
Engineers develop AI tool to design peptides that turn signals on or off
To develop new and better peptides, the short amino acid strings behind medicines like GLP-1 drugs, researchers have used AI to generate candidates and to predict their properties.
Scientists improve the analgesic efficacy of morphine
Scientists improve the analgesic efficacy of morphine
Scientists at the Department of Cell Biology of the University of Malaga have taken a step forward in the search for more effective treatments for pain with a new study that advances efforts to mitigate the addictive effects of morphine—one of the main drugs used for this purpose
Foto: Google DeepMind / Pexels
Demystifying the molecular mechanisms of general anesthesia
Researchers at Weill Cornell Medicine and Birkbeck, University of London, have identified a site where a commonly used anesthetic binds to sodium ion channels, revealing a molecular mechanism that may explain how these drugs dampen communication between neurons. Ion channels are
Epigenetic therapy shows promise against treatment-resistant AML
Researchers at The University of Texas MD Anderson Cancer Center have discovered that an investigational epigenetic therapy remained effective in treatment-resistant acute myeloid leukemia (AML) by activating the Hippo pathway, a tumor-suppressing pathway linked to cancer growth
Ibuprofen safely dampens inflammatory markers in 28-patient drug-resistant tuberculosis tr
The Experimental Tuberculosis Unit (UTE) at the Germans Trias i Pujol Research Institute (IGTP) has published in Nature Communications the results of a phase IIa pilot clinical trial assessing ibuprofen as a host-directed therapy in patients with pre-extensively drug-resistant tu
Study finds obesity 'fuels' leukemia, but a combo using popular weight-loss drugs may stop
Study finds obesity 'fuels' leukemia, but a combo using popular weight-loss drugs may stop
Obesity can act as fuel for leukemia, according to a study led by Indiana University School of Medicine scientists. To help patients facing aggressive blood cancers overcome this metabolic risk, researchers identified a potential treatment strategy that combines popular weight-lo
US study suggests GLP-1 RA drugs are associated with small increase in ischemic optic neur
US study suggests GLP-1 RA drugs are associated with small increase in ischemic optic neur
A target trial emulation found that people with type 2 diabetes who started glucagon-like peptide-1 receptor agonist (GLP-1RA) therapy had a slightly higher risk of ischemic optic neuropathy (ION), a rare condition involving reduced blood flow to the optic nerve that can cause su
A natural compound steps into the estrogen arena
Uterine fibroids and endometriosis are two of the most common gynecologic diseases, affecting 15% to 80% of women of childbearing age. Existing treatments—hormonal drugs and selective estrogen receptor modulators—have side effects and cannot reliably prevent recurrence. This is w
New York data reveal substance use in 44% of pedestrian deaths
New York data reveal substance use in 44% of pedestrian deaths
In New York state, 44% of pedestrian deaths involved alcohol or drug use by the pedestrian, according to a retrospective analysis published online in the journal Injury Prevention. Pedestrian injuries are the seventh-leading cause of injury-related death in New York state. There
Combination treatment harnesses cellular recycling system to fight multiple myeloma
New research from VCU Massey Comprehensive Cancer Center provides evidence for a combination treatment strategy that uses cells' waste-removal functions to target multiple myeloma. The findings, published recently in Cell Death & Disease, show how an experimental targeted protein
New cancer drug shows promise in mesothelioma trial
New cancer drug shows promise in mesothelioma trial
Mesothelioma is a rare but aggressive cancer, usually caused by exposure to asbestos. Inhaled asbestos fibers become lodged in the lungs, causing inflammation that can lead to tumor formation decades later. Worldwide, about 30,000 people are diagnosed with mesothelioma each year.