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Modest sleep loss linked to weight gain in adults with high cardiometabolic risk
A pooled analysis of two randomized trials found that decreasing sleep by just 1.5 hours each night was associated with increases in body weight, waist circumference and sedentary time in adults with elevated cardiometabolic risk.
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Tumor on a chip reveals how pancreatic cancer hijacks immune cells in real time
A new "tumor-on-a-chip" model is giving scientists a live look at how pancreatic cancer can recruit the body's own immune cells to help tumors survive. Researchers say the findings, published in Biofabrication, reveal possible new targets to weaken the cancer's defenses and make
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Drug candidate treats severe fatty liver disease by protecting the gut in animal models
Researchers discovered that a potential drug developed at Michigan Medicine treats severe fatty liver disease by improving gut health, according to a study published in The Journal of Clinical Investigation.
New approach could expand CAR T therapy from blood cancers to solid tumors
New approach could expand CAR T therapy from blood cancers to solid tumors
Researchers at the University of Pittsburgh, UPMC Hillman Cancer Center and the National Cancer Institute report that combining CAR T cell immunotherapy with a targeted radiopharmaceutical significantly improved tumor regression in preclinical models of neuroblastoma, a rare and
First AI agent and risk prediction model for precision diabetes management
First AI agent and risk prediction model for precision diabetes management
A research team at The Hong Kong Polytechnic University (PolyU) has developed Hong Kong's first "AI Agent for Precision Diabetes Management—PIPE-AI" (AI Agent), designed specifically for Asian populations, together with a related disease risk prediction model. Leveraging artifici
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Modern IVF achieves higher success rates with single embryo transfer, major study finds
Modern IVF treatment can now achieve substantially higher success rates than historical approaches while dramatically reducing twin and triplet pregnancies, according to new research presented at the 42nd Annual Meeting of the European Society of Human Reproduction and Embryology
Como o azeite pode ser um aliado no processo de emagrecimento?
Como o azeite pode ser um aliado no processo de emagrecimento?
Azeite extravirgem: saudável e cheio de benefícios, mas a moderação é crucial para o emagrecimento. Entenda o impacto das calorias.
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AI-guided CRISPR uncovers oxytocin receptor as unexpected psoriasis drug target
Biohub researchers have performed what they believe is the first genome-wide CRISPR study of primary human adult skin cells, then used an AI model to mine the results for overlooked drug targets for psoriasis. They found an unlikely candidate: the receptor for oxytocin, a hormone
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New model reveals how disability caregiving reshapes parents' lives over decades
Researchers are sounding the alarm on the long-term impact of caring for children with developmental disabilities in the absence of proper societal supports across the life course. A new conceptual study, published in the Journal of Family Theory & Review, proposes a new model fo
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Alcohol drives opposite brain circuit changes in amyloid and tau Alzheimer's models
Alcohol use has been associated with an increased risk of cognitive decline and dementia. But new research from Texas A&M University's Naresh K. Vashisht College of Medicine at Texas A&M Health suggests the relationship between alcohol and Alzheimer's disease is more complicated
Moderate, home-based exercise found safe for aortic dissection survivors
Moderate, home-based exercise found safe for aortic dissection survivors
A multicenter clinical trial led by UTHealth Houston has found that survivors of aortic dissection can participate in moderate-intensity exercise at home without increasing the risk of recurrent aortic events. The study is published in Circulation: Population Health and Outcomes.
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Gut bacteria linked to malnutrition may pass to younger generations
A study led by researchers at Washington University School of Medicine in St. Louis suggests that an intestinal disorder linked to malnutrition and stunted growth may be transmitted from one generation to the next via the small intestinal microbiome. Analyzing mouse models of the