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469 notícias encontradas para "these"
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Artemisinin resistance is rising in East Africa—leaving anti-malarials at risk of failure
Resistance to the main drug in front-line malaria treatments is becoming more widespread across East Africa, according to new research by Imperial College London. The study, published in The Lancet Infectious Diseases, maps the rise in artemisinin resistance in the region and sug
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Demystifying the molecular mechanisms of general anesthesia
Researchers at Weill Cornell Medicine and Birkbeck, University of London, have identified a site where a commonly used anesthetic binds to sodium ion channels, revealing a molecular mechanism that may explain how these drugs dampen communication between neurons. Ion channels are
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New insights into neuron–microglia interactions during brain aging
Researchers at the University of Tsukuba have identified small nuclear fragments known as micronuclei while studying neurons in aged mice. They demonstrated that microglia—the brain's resident immune cells—take up these micronuclei, leading to changes in microglial morphology and
'Double-donut' structure of SPOP protein reveals mechanism of unexplained cancer mutations
Mutations to the protein SPOP are widespread in cancer, yet many remain poorly understood. To address this gap, St. Jude Children's Research Hospital scientists obtained structures of SPOP in both the presence and absence of these mutations. Their work captured the fine balance b
Raman imaging applied to cardiac tissue of Fabry disease model reveals molecular map of li
How are disease-relevant molecules distributed within tissue? What changes occur even before they become visible under the microscope? Questions such as these are crucial for early diagnosis and targeted treatment in many diseases. Researchers at the Leibniz-Institut für Analytis
Mediterranean diet compounds may aid nerve cells as brains age, review finds
Natural plant compounds known as polyphenols, found in berries, tea, cocoa, coffee and extra-virgin olive oil, may positively influence biological processes linked to Alzheimer's disease and other disorders characterized by the gradual loss of nerve cells, according to a review b
Alcohol intoxication, stress in adolescence linked with long-term impairments
Repeated alcohol intoxication or exposure to stress appears to change how adolescent brains respond to danger. These changes persist into adulthood. In a study published in Alcohol: Clinical and Experimental Research, adolescent mice repeatedly exposed to alcohol or stress were l
Poor-quality sleep involves different parts of the brain, depending on age
Have trouble sleeping? The reason may depend in part on your age. A recent study that included psychology researchers from Binghamton University investigates how poor sleep alters brain communication across the adult lifespan, specifically examining how these changes vary by age
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Why some people are more prone to negative emotions than others
Why are some people particularly prone to anxiety, worry or stress, while others remain more composed? An international study led by the Central Institute of Mental Health (CIMH) shows that the amygdala—previously considered central to these processes—apparently does not explain
Most community health centers provide prenatal care, but one-third still lack services
Most community health centers provide prenatal care, but one-third still lack services
A new national study provides the first comprehensive look at prenatal care services offered by federally qualified health centers (FQHCs), revealing that while these safety-net providers play a critical role in caring for low-income and racially diverse pregnant populations, sig
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Brain-computer training sharpens detection of tiny movement errors in five days
The brain uses visual cues to coordinate muscle movement. When motor commands and sensory feedback are out of alignment, visuo-motor errors occur. Rapid perception of these errors allows for correction, which is important in many aspects of life—from preventing falls among older
French court reduces graft sentence for Marine Le Pen
Under the appeals verdict, the far-right leader may be able to run for president in 2027, though she would have to wear an ankle monitor. She has previously said she would not stand for election under these conditions.