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A molecule linked to chronic inflammation disrupts the brain's ability to create new neurons, uncovering a pathway with therapeutic potential for neurodegenerative diseases and neurological conditions. The King's College London study, published in Nature Communications, offers in

The human brain contains billions of neurons, specialized nerve cells that communicate with each other via electrical and chemical signals. Every neuron is made up of its body (i.e., soma), where most cellular processes occur; a long projection called an axon that sends signals t

If you are crossing an unfamiliar room in the dark, you may grope around a bit to get a sense of your space. But for many animals, feeling out a space comes more naturally. A mouse, for instance, can efficiently navigate in the dark just by grazing its whiskers against walls and

It's a fact of life that the electrical activity of neurons will vary during the same task, even when the ultimate outcome is the same. A new study shows that a lot of ongoing fluctuations in the brain's activity can be explained by the influence local electric fields exert on th

Accumulation of DNA damage in the brain's neurons may contribute to the development of Alzheimer's disease. New research in FEBS Open Bio demonstrates the therapeutic potential of a drug that targets this process.

What makes the human brain capable of language, imagination, mathematics and invention? For many years, the prevailing view was that the secret of human intelligence lay mainly in scale: the sheer number of neurons in the human brain—close to 100 billion—and the vast network of c

A research team led by Professor Il-Joo Cho of Korea University College of Medicine has developed a novel brain implant capable of bidirectionally modulating neural activity using temperature, opening new possibilities for next-generation brain-computer interfaces (BCIs) and trea

After the storm comes the calm. But contrary to the famous proverb, the brain's neurons enter a period of calm before the neuronal storm that is an epileptic seizure. An international team of researchers has now demonstrated that this silencing of neurons can serve as a marker ca

Interim clinical findings from the first Phase I/IIa trial using autologous-induced pluripotent stem cell (iPSC)-derived dopamine neuron precursor cells, along with the novel quality-control tools developed to manufacture these individualized therapies, have been presented by Jea

DZNE researchers have uncovered a mechanism that determines why a neuron usually forms a single, long extension called an "axon"—a phenomenon that is fundamental to how our brain functions. Contrary to the common view that external cues drive axon formation, the team of scientist

A new brain imaging study led by researchers at the Center for Addiction and Mental Health (CAMH), published in eBioMedicine, provides the strongest evidence to date that long COVID is associated with injury to dopamine-releasing neurons in the brain—a finding that may explain sy

Researchers at Weill Cornell Medicine and Birkbeck, University of London, have identified a site where a commonly used anesthetic binds to sodium ion channels, revealing a molecular mechanism that may explain how these drugs dampen communication between neurons. Ion channels are