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131 notícias encontradas para "path"
Pediatric recommendations for preventing and controlling Candida auris released
The Society for Healthcare Epidemiology of America (SHEA) has released a new consensus statement providing pediatric-specific recommendations for the infection prevention and control of Candida auris (also referred to as Candidozyma auris), a multidrug-resistant fungal pathogen a
Gut-homing antibodies help protect against norovirus, paving path for new vaccines, therap
As the leading cause of viral gastroenteritis worldwide, norovirus is an all too familiar ailment. Its telltale digestive upset—not to mention its reputation for being notoriously contagious—has earned it the nicknames "winter vomiting bug" and "stomach flu." Yet despite millions
Eliminating cancer cells that survive KRAS inhibition: A potential way to prevent relapse
Our cells rely on tightly regulated signaling pathways to control when they grow, divide and survive. When these regulatory systems are disrupted, cells can acquire the ability to grow uncontrollably and become cancerous. One of the most important cancer-related signaling molecul
Targeting cannabinoid receptors in bladder sensory pathways may alleviate pain of cystitis
The burning pain associated with cystitis affects millions of people around the world, and it can take days or even years for some patients to find relief from bladder pain, infection-related symptoms and the constant need to urinate. A new study led by Flinders University publis
New Tfr cell model uncovers molecular switches that restrain antibody responses
New Tfr cell model uncovers molecular switches that restrain antibody responses
For the immune system to effectively combat pathogens, antibody responses must be precisely controlled. So-called follicular regulatory T cells (Tfr cells) play a key role in this process by limiting excessive immune responses and helping to maintain immune tolerance. Researchers
Opposing protein pathways steer skin stem cells toward renewal or repair
Two proteins with opposing functions orchestrate the development and maintenance of healthy skin, Stanford Medicine researchers have found. Modulating their activity with topical drugs could reduce inflammation, aid wound healing and slow or halt the growth of skin cancer, the re
Identifying immune pathways driving aggressive brain cancers
A new study has uncovered a key mechanism that helps one of the deadliest brain cancers evade the immune system, according to the study published in The Journal of Clinical Investigation.
Women with Parkinson's disease may show more Alzheimer's-related brain changes than men
Women with Parkinson's disease may be more vulnerable to Alzheimer's-related changes in the brain than men, according to new research presented at the European Academy of Neurology (EAN) Congress 2026. Parkinson's disease and Alzheimer's disease frequently co-occur in older adult
Neural pathways reveal a push-pull system for coordinating goal-directed behavior in mice
Most of the tasks that humans complete daily entail carefully coordinating movements and tracking progress made toward a desired goal. Past studies have highlighted the role of the basal ganglia (BG), a set of interconnected structures deep within the brain, in the selection, con
Foto: Tara Winstead / Pexels
Emerging mRNA vaccine strategies target cancer and pathogenic viruses in potent new ways
The technology that gave the world mRNA COVID vaccines is being tested in a variety of new ways, and emerging research reveals that a crucial T-cell population can be reprogrammed in animal models by reimagining the science that was introduced to the public at the height of the p
Foto: Nataliya Vaitkevich / Pexels
Unlocking diabetes' secrets: Pediatric organ donors help map a path to a cure and preventi
The autoimmunity associated with type 1 diabetes often begins in the first years of life, and the diagnosis of type 2 diabetes is rapidly rising among children and teens.
Kidney cancer gene reveals an unexpected weakness and a new path for treatment
A common genetic mutation that helps some kidney cancers survive may also expose an unexpected weakness, one that MUSC Hollings Cancer Center researchers hope to transform into a new treatment strategy. In a study published in Cancer Research, Aguirre de Cubas, Ph.D., and colleag