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131 notícias encontradas para "path"
AI-guided pathology analysis can help predict immunotherapy response in rare cancers
Researchers from The University of Texas MD Anderson Cancer Center demonstrated that an artificial intelligence (AI)-based analysis of tumor biopsies can predict responses to immunotherapy in a study of patients with rare cancers, published in the Journal for ImmunoTherapy of Can
Personalized disease-in-a-dish can improve a pancreatitis patient's therapeutic path
Around 3 million people worldwide struggle with chronic pancreatitis, a condition in which the pancreas becomes inflamed, scarred and painful. There is no cure for chronic pancreatitis, and it is difficult to alter the disease trajectory after onset.
Baby-led weaning: A solid approach to infant nutrition
When it's time to add solid food to a baby's diet, is it best to spoon-feed purees—the conventional approach—or to allow the baby to feed herself soft finger foods? The second path, called baby-led weaning, has exploded in popularity in the past decade, yet many parents and careg
Identification of new molecular markers for multiple myeloma paves path for more precise t
Researchers at Cima and Clinica Universidad de Navarra have identified new molecular mechanisms underlying multiple myeloma. This type of hematologic cancer, which affects the bone marrow, is characterized by its resistance to treatment, leading to relapses in patients. The resea
Parkinson's patients undergoing deep brain stimulation show little to no cortical Lewy pat
Researchers at the Icahn School of Medicine at Mount Sinai have found that patients with Parkinson's disease undergoing deep brain stimulation (DBS) show little to no Lewy pathology in the prefrontal cortex at the time of their DBS surgery, despite often having longstanding, clin
New drug unlocks elusive immune receptor, opening path toward motor neuron disease treatme
University of Queensland researchers have developed a drug that activates a hard-to-target immune receptor—a breakthrough that could lead to new treatments for neurodegenerative conditions like motor neuron disease (MND).
New virus catalog reveals which pathogens pose the greatest threat
In a typical year, scientists discover two or three viruses that have never been seen in people before. The number fluctuates, but the trend has been fairly steady since the 1960s.
Fibronectin pathway may drive Marfan aortic damage, opening new drug targets
A new study published in Nature Communications identifies a molecular signaling pathway that contributes to the development of life-threatening aortic aneurysms and dissections in Marfan syndrome, a genetic disorder affecting connective tissue. The findings provide new insight in
Iron helps trigger asthma-linked airway inflammation by activating pathway
Chinese researchers have revealed the key role of iron in initiating allergic airway inflammation. The study, which was published in Cell, was conducted by a team led by Prof. Sun Bing from the Center for Excellence in Molecular Cell Science (Shanghai Institute of Biochemistry an
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1 in 5 relatives of breast and ovarian cancer patients in Estonia carry dangerous cancer-l
In 2013, Angelina Jolie inspired a wave of testing for pathogenic variants of the gene BRCA1 by announcing that she carried a variant that left her at such high risk of breast cancer that she chose a preventive mastectomy. Many people with similar gene variants won't need risk-re
TNF-alpha blocks new neurons in hippocampus, reveals inflammation pathway
A molecule linked to chronic inflammation disrupts the brain's ability to create new neurons, uncovering a pathway with therapeutic potential for neurodegenerative diseases and neurological conditions. The King's College London study, published in Nature Communications, offers in
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Key gut protein balances immune protection and tolerance
A protein produced by gut immune cells orchestrates both immune protection against pathogens and immune tolerance of gut bacteria, according to a study led by Weill Cornell Medicine investigators. The discovery illuminates the complex biology of the gut immune system and could le