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Lyme disease can be easiest to treat in its earliest stages, but current tests often miss infections during that critical window and cannot tell whether bacteria are still present or were cleared years ago. New research led by Tufts University School of Medicine suggests that a g

A research team in Korea has developed a vaccine technology that delivers long-lasting immune protection from a single dose by applying the powerful underwater adhesion mechanism of mussels. The work is drawing attention not only for reducing the burden of repeat vaccination, but

New research led by Mass General Brigham investigators suggests that the Bacillus Calmette-Guérin (BCG) vaccine—which is delivered through the skin to prevent tuberculosis—may remodel the human brain's immune environment, offering a potential biological explanation for previously

Researchers at Tel Aviv University's Gray Faculty of Medical and Health Sciences have uncovered how a natural and essential immune system process can be hijacked to promote cancer progression. In a new study, the research team developed an advanced technology that enabled it to t

University of Queensland researchers have developed a drug that activates a hard-to-target immune receptor—a breakthrough that could lead to new treatments for neurodegenerative conditions like motor neuron disease (MND).

Primary CNS lymphoma is a rare cancer that arises from malignant white blood cells. Affected individuals develop tumors in the brain and, more rarely, in the spinal cord, the eyes or within the cerebrospinal fluid. These lymphomas can occur in people with weakened immune systems,

Researchers at Karolinska Institutet have uncovered how serotonin-related metabolism helps regulate an understudied immune cell involved in allergic inflammation. The study, published in the journal Allergy, adds to knowledge about how allergic immune responses may be maintained

For most women, the body begins to change dramatically in their 40s or 50s. This transition, known as menopause, is defined as 12 consecutive months without a menstrual period, marking the end of the reproductive years. While researchers are aware of the functions the ovaries per

Cancer immunotherapy drugs known as immune checkpoint inhibitors (ICIs) can be miracle drugs for cancer patients, curing some and turning deadly disease into a manageable chronic condition in others. But these drugs work for only a subset of patients, with few indications why—a k

Unlike accidental cell death, some cells can actively decide to die through a controlled process. This is called programmed cell death and can occur in different forms, including apoptosis and necroptosis. Cells use this process when they are damaged, stressed, becoming cancerous

In the event of a severe heart attack, immature immune cells are released into the bloodstream from the bone marrow. A research team led by the University of Münster has demonstrated that the maturity level of neutrophils can be used to determine the short-term risk of death, and

A novel vaccination strategy against certain malignant brain tumors could fundamentally improve treatment for patients. Researchers from the German Cancer Research Center (DKFZ), Mannheim University Medical Center, Heidelberg University Hospital and numerous partner institutions