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Fatty liver drives a more dangerous form of colorectal cancer spread, study reveals
Researchers at VIB and KU Leuven, with international partners, have uncovered how fatty liver disease can fuel the most aggressive form of metastatic colorectal cancer. The findings, which appear in the journal Nature, not only explain why some patients face dramatically poorer o
Cancer also knows how to wait: Study uncovers the hidden step between mutation and tumor b
Cancer also knows how to wait: Study uncovers the hidden step between mutation and tumor b
The development of cancer is not a process triggered immediately by the emergence of an oncogenic mutation. There is growing evidence for the existence of an intermediate phase—hitherto poorly defined—in which mutated cells remain in a latent state, "accumulating the potential ne
Tumors hijack macrophages after they clear dead cells, real-time tracking reveals
Researchers at Tel Aviv University's Gray Faculty of Medical and Health Sciences have uncovered how a natural and essential immune system process can be hijacked to promote cancer progression. In a new study, the research team developed an advanced technology that enabled it to t
Dynamic protein behavior drives blood-brain barrier specialization, study reveals
A study led by researchers at the Institute for Bioengineering of Catalonia (IBEC), in collaboration with the Proteomics Platform of the Institute for Research in Biomedicine (IRB Barcelona), has uncovered a key mechanism that helps define how the blood-brain barrier functions—no
Foto: Tima Miroshnichenko / Pexels
How serotonin may help drive long-term allergic inflammation through overlooked immune cel
Researchers at Karolinska Institutet have uncovered how serotonin-related metabolism helps regulate an understudied immune cell involved in allergic inflammation. The study, published in the journal Allergy, adds to knowledge about how allergic immune responses may be maintained
Common brain cancer mutation changes DNA shape to drive progression, exposing therapeutic
Common brain cancer mutation changes DNA shape to drive progression, exposing therapeutic
A new study from researchers at The University of Texas MD Anderson Cancer Center has uncovered how one of the most common genetic alterations in glioma rewires the cancer cell genome to fuel tumor progression, suggesting a potential new therapeutic strategy for patients with ATR
Cancer screening rates vary across sexual orientation and gender identity
Cancer screening rates vary across sexual orientation and gender identity
New research has uncovered persistent disparities in preventive cancer care across different sexual orientation and gender identity (SOGI) populations. The study, published in Cancer, found particular concern for cervical and breast cancer screening.
Researchers uncover possible cause of muscle pain from widely used cholesterol medication
Researchers uncover possible cause of muscle pain from widely used cholesterol medication
Millions of people rely on statins, a medication used to lower cholesterol and reduce the risk of heart attack and stroke. But for some, the drugs come with an unwelcome trade-off: muscle pain, weakness and exercise intolerance that can make it difficult to continue treatment. No
Study reveals how the uterine microbiome may impact pregnancy success
Study reveals how the uterine microbiome may impact pregnancy success
Researchers from Trinity College Dublin have uncovered new evidence that the communities of bacteria living in the uterus may play an important role in determining whether pregnancy is successful following assisted reproductive technologies (ART) such as IVF. Among the key findin
Scientists uncover two neuronal circuits orchestrating muscle autophagy
Scientists uncover two neuronal circuits orchestrating muscle autophagy
Autophagy is the process by which cells remove damaged proteins, recycle worn-out organelles (e.g., mitochondria), clear cellular waste and provide nutrients during stress. Autophagy is essential for muscles because they are constantly under mechanical stress. If autophagy is too
TNF-alpha blocks new neurons in hippocampus, reveals inflammation pathway
A molecule linked to chronic inflammation disrupts the brain's ability to create new neurons, uncovering a pathway with therapeutic potential for neurodegenerative diseases and neurological conditions. The King's College London study, published in Nature Communications, offers in
Advanced imaging uncovers 3D nerve architecture inside rat knee joints, could yield clarit
Temporomandibular disorders (TMDs) are a group of more than 30 conditions that cause pain and dysfunction in the jaw. So what could a small tissue sample from a rat's knee have to do with treating them?