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286 notícias encontradas para "cell"
Robust colorectal cancer signature identified in large-scale microbiome study
Researchers have long suspected that the gut microbiome—the community of bacteria and other microorganisms living in the intestine—is closely linked to colorectal cancer. In a new study published in Cell Host & Microbe, an international group of researchers from the Mi-EOCRC cons
What a 'silenced' chromosome can tell us about autoimmunity
What a 'silenced' chromosome can tell us about autoimmunity
Systemic lupus erythematosus (SLE), the most common form of lupus, is an autoimmune disorder that occurs more frequently in women. Having multiple X chromosomes has been associated with an increased risk of developing lupus; however, the reason for this link is still not fully un
Skin renews despite 60% to 70% fibroblast depletion in mice, challenging long-held assumpt
Human skin is constantly rebuilding itself. Every few weeks, the outermost layers shed and are replaced by new cells pushed up from the base. For decades, scientists believed this renewal depended heavily on fibroblasts, a class of supportive cells nestled in the deeper layer of
Foto: Turgay Koca / Pexels
Aging reshapes the ovary long before reproductive function ends
Aging affects every organ in the body, yet we still know little about how the ovary changes over time. In a new study published in Nature Aging, Yale researchers created one of the most detailed maps of the aging ovary to date, examining how its cellular organization changes acro
Hidden mechanism driving joint tissue growth in rheumatoid arthritis has been found
Hidden mechanism driving joint tissue growth in rheumatoid arthritis has been found
Researchers at Hospital for Special Surgery (HSS) have identified a specialized population of immune cells that plays a central role in driving abnormal tissue growth in rheumatoid arthritis (RA), offering new insight into disease progression and potential treatment strategies. T
New technology helps reveal how the heart generates cells with regenerative potential
New technology helps reveal how the heart generates cells with regenerative potential
Two research teams at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) have developed a pioneering technique in Spain to characterize the proteome of individual cardiomyocytes—the cells responsible for heart contraction.
Immune cell–fibroblast crosstalk may be the key trigger of autoimmune diseases
Immune cell–fibroblast crosstalk may be the key trigger of autoimmune diseases
In autoimmune disorders, immune cells targeting "self" proteins are mistakenly activated, resulting in abnormal expansion and responsiveness. These disorders are known to reduce patients' quality of life over a prolonged period. This can be attributed to CD4+ T cells, which play
Foto: Jakub Zerdzicki / Pexels
Mapping the hidden rules of a key immune sensor
The immune system depends on molecular alarms that detect danger inside cells. One of these alarms is STING, short for "stimulator of interferon genes." STING helps cells respond to infections, damaged DNA and cancer. When it activates at the right time, it helps protect the body
CAR T cell therapy leads to 10-year remissions in B-cell lymphoma patients
CAR T cell therapy leads to 10-year remissions in B-cell lymphoma patients
After a median follow-up of 10 years, more than one-third of patients with large B-cell lymphoma and nearly half of patients with follicular lymphoma who received a single infusion of tisagenlecleucel—the CAR T-cell therapy developed by Carl June, MD, that would go on to become t
Foto: Darina Belonogova / Pexels
Eliminating cancer cells that survive KRAS inhibition: A potential way to prevent relapse
Our cells rely on tightly regulated signaling pathways to control when they grow, divide and survive. When these regulatory systems are disrupted, cells can acquire the ability to grow uncontrollably and become cancerous. One of the most important cancer-related signaling molecul
Foto: Paul Seling / Pexels
Video of tiny vessels in the eye assessed by AI may replace needle sticks for anemia scree
A new collaborative study by Tel Aviv University and Sheba Medical Center marks a significant advance toward noninvasive blood testing, one of the most significant unmet needs in the market. The researchers have developed an artificial intelligence–based system capable of assessi
Vulnerable ALS neurons reveal molecular warning signs before cell death begins
A new study from the Knight Initiative for Brain Resilience researchers may help explain an enduring mystery about amyotrophic lateral sclerosis (ALS): why the disease kills off some of the brain and spinal cord's movement-controlling neurons while others show greater resilience.