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Brain glutamate changes could link cannabis use to a higher risk of psychosis
Cannabis, commonly known as marijuana, is a plant that contains psychoactive compounds that can temporarily alter people's brain activity and perceptions. While the consumption of this plant for medical or recreational purposes is now legal in a number of regions worldwide, past
Economic evaluation supports prophylactic naldemedine for opioid-induced constipation in c
Although opioids remain indispensable for pain relief in patients with advanced cancer, their use frequently results in OIC, which can substantially reduce quality of life and, in some cases, compromise the continuation of optimal pain management. Naldemedine, a peripherally acti
Vaginismo: quando informação e acolhimento fazem a diferença
O vaginismo afeta a sexualidade feminina pela contração pélvica. Entenda o que é, suas causas e os tratamentos eficazes.
Mouse study uncovers how transcription factors HIF1α and HIF2α regulate different aspects
Skeletal muscles—responsible for movement, joint stabilization and postural support—are highly metabolically active and heavily reliant on oxygen during physical activity. However, conditions such as high-intensity exercise or sustained exertion frequently expose skeletal muscles
Student-led study aims to improve diagnosis of early-onset dementia, a frequently misdiagn
Research led by a University of Sydney medical student could enable earlier and more accurate diagnosis of behavioral variant frontotemporal dementia—one of the most commonly misdiagnosed forms of early-onset dementia, which can begin as early as a person's late 40s and is often
5 escolhas na alimentação que favorecem o emagrecimento no inverno
Manter o peso no frio é possível! Dicas de nutricionista para adaptar o cardápio de inverno sem abrir mão do sabor e do bem-estar.
Scientists uncover genetic clues from a tumor-prone reptile that could advance cancer rese
A new study led by experts at the University of Nottingham suggests a pet gecko with an unusually high risk of tumors may be a promising model for understanding how cancer develops and spreads. The findings of the study, which are published in BMC Biology, could help explain why
As heat waves loom, scientists wonder how humans will adapt
Temperatures are set to soar in the US around the July 4 holiday, a week after Europe struck new records. With experts predicting more intense and more frequent heat waves in the future, can our bodies adapt?
A reforma tributária e as limitações constitucionais ao poder de tributar
A reforma tributária positivada pela Emenda Constitucional 132/2023 está produzindo transformações profundas, não apenas na estrutura dos tributos sobre o consumo, mas também no plano das garantias constitucionais dos contribuintes. Tema frequentemente tratado como um pano de fun
O Direito Administrativo da reforma tributária: eles, os servidores
Quem executará as competências do Comitê Gestor? O recorte ajuda a contextualizar a pauta dentro de Geral.
O resgate da liberdade nos labirintos da coisa julgada
O sistema prisional frequentemente reduz o indivíduo a uma mera folha de antecedentes e a um cálculo matemático expresso em anos, meses e dias. Por trás das frias engrenagens judiciais, contudo, pulsa a realidade de homens e mulheres submetidos a sanções que, não raro, desrespeit