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134 notícias encontradas para "path"
Foto: Anna Tarazevich / Pexels
1 in 5 relatives of breast and ovarian cancer patients in Estonia carry dangerous cancer-l
In 2013, Angelina Jolie inspired a wave of testing for pathogenic variants of the gene BRCA1 by announcing that she carried a variant that left her at such high risk of breast cancer that she chose a preventive mastectomy. Many people with similar gene variants won't need risk-re
Admin Recifes 15/07/2026 1
TNF-alpha blocks new neurons in hippocampus, reveals inflammation pathway
A molecule linked to chronic inflammation disrupts the brain's ability to create new neurons, uncovering a pathway with therapeutic potential for neurodegenerative diseases and neurological conditions. The King's College London study, published in Nature Communications, offers in
Admin Recifes 15/07/2026 1
Foto: www.kaboompics.com / Pexels
Key gut protein balances immune protection and tolerance
A protein produced by gut immune cells orchestrates both immune protection against pathogens and immune tolerance of gut bacteria, according to a study led by Weill Cornell Medicine investigators. The discovery illuminates the complex biology of the gut immune system and could le
Admin Recifes 15/07/2026 1
Researchers chart a genetic path to diagnosing pulmonary fibrosis and predicting outcomes
Researchers chart a genetic path to diagnosing pulmonary fibrosis and predicting outcomes
Researchers have validated a genetic scoring tool that may help physicians diagnose idiopathic pulmonary fibrosis and identify which patients are at greatest risk for severe outcomes, including death or the need for a lung transplant. The findings come from a new international st
Admin Recifes 15/07/2026 1
Gut bacteria boost immune system, help send vitamin A to T cells
Scientists at UT Southwestern Medical Center have discovered that gut bacteria help regulate the development of the body's immune system by directing the movement of vitamin A through a previously unrecognized cellular network. The preclinical findings, published in Cell Host & M
Admin Recifes 15/07/2026 1
Foto: Merlin Lightpainting / Pexels
Team discovers metabolic pathway in cell nucleus that helps cancer progress
A team at Roswell Park Comprehensive Cancer Center has identified a novel metabolic pathway that plays a key role in enabling cancer to progress through gene activation. In a new study published in the journal Nature Communications, the researchers show that shutting down the pat
Admin Recifes 15/07/2026 1
After amyloid plaques form, tau and alpha-synuclein pathology rises in mice
After amyloid plaques form, tau and alpha-synuclein pathology rises in mice
The aging brain frequently harbors multiple protein pathologies that contribute to Alzheimer's, Parkinson's and other neurodegenerative diseases. But how do these problematic proteins interact with each other, and could these interactions inform future therapies? Researchers at T
Admin Recifes 15/07/2026 1
Hidden pathway drives COVID-19 infection, triggers damaging inflammation in the lungs
Hidden pathway drives COVID-19 infection, triggers damaging inflammation in the lungs
New research has uncovered a hidden pathway that allows COVID-19 to infect the immune system and trigger damaging inflammation in the lungs. The study by La Trobe University and WEHI researchers found SARS-CoV-2, the virus that causes COVID-19, can hide inside tiny fragments of d
Admin Recifes 15/07/2026 1
Epigenetic therapy shows promise against treatment-resistant AML
Researchers at The University of Texas MD Anderson Cancer Center have discovered that an investigational epigenetic therapy remained effective in treatment-resistant acute myeloid leukemia (AML) by activating the Hippo pathway, a tumor-suppressing pathway linked to cancer growth
Admin Recifes 15/07/2026 1
Researchers reveal immune mechanisms that drive development of rare allergic stomach disea
Researchers reveal immune mechanisms that drive development of rare allergic stomach disea
Researchers at Tel Aviv University have developed one of the first experimental models that faithfully reproduces eosinophilic gastritis (EoG), a rare but increasingly recognized allergic disease of the stomach. Using this model, they identified the immune pathways responsible fo
Admin Recifes 15/07/2026 1
Foto: Anna Tarazevich / Pexels
Signaling pathway may help predict immunotherapy response in glioblastoma
Northwestern Medicine scientists have uncovered a biological mechanism that helps explain why most patients with glioblastoma fail to respond to immunotherapy, according to their study published in Nature Communications.
Admin Recifes 15/07/2026 1
Amyloid-clearing treatment may curb tau buildup for years in Alzheimer's brain
An analysis of the brain of a deceased Alzheimer's disease (AD) clinical trial participant found that regions where an anti-amyloid therapy successfully cleared amyloid plaques showed little to no evidence of tau tangles, a hallmark of AD closely linked to neurodegeneration and c
Admin Recifes 15/07/2026 1
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