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1,431 notícias encontradas para "target"
Hidden pocket reveals new way to target prostate cancer's 'undruggable' ERG protein
Hidden pocket reveals new way to target prostate cancer's 'undruggable' ERG protein
In the United States, prostate cancer is a leading cause of cancer-related disease and death in men. About half of prostate cancer cases in patients of European ancestry have a gene rearrangement in which the genes TMPRSS2 and ERG are fused together. This causes the ERG protein t
Foto: Thirdman / Pexels
Anticancer 'nanoswitch' technology shows promise in animal model of triple-negative breast
A research team led by Professor Yoosoo Yang (Department of Integrative Biotechnology) of Sungkyunkwan University, in collaboration with the Korea Institute of Science and Technology (KIST) and Incheon National University, has developed a next-generation anticancer immunotherapy
Foto: Turgay Koca / Pexels
Novel microenvironment-targeted therapy for bone marrow recovery after injury
A healthy bone marrow (BM) produces nearly all types of cells in our blood. Many blood disorders occur when hematopoietic stem cells (HSCs) in the BM malfunction. Treatment with radiation or chemotherapy for many blood disorders and cancers can, as a side effect, deplete not only
Inhibiting protein to treat myeloproliferative neoplasms shows preclinical promise
Inhibiting menin, a protein that supports leukemia growth and is already targeted to treat some forms of leukemia, also holds promise for treating myeloproliferative neoplasms. A new study from scientists at St. Jude Children's Research Hospital showed that inhibiting menin signi
New clues raise hopes for better treatment of RSV in babies
Future therapies for respiratory syncytial virus (RSV) must target both the virus and the immune response to ensure babies get the best possible outcomes, a new study by researchers at UCL and Great Ormond Street Hospital for Children (GOSH) finds.
Foto: Anna Tarazevich / Pexels
Novel technology could aid targeted lung cancer treatment
Scientists have developed a new method for accurately predicting gene changes that cause lung cancer, without the need for slower, more expensive lab techniques. The technology was able to identify specific genetic changes with high accuracy, offering a potentially faster, more e
Can infants detect voices in noisy environments? New research says yes
In noisy environments, organisms differentiate sounds they want to detect from interfering noise to improve their perception of target sounds. This process is widely conserved across species, including birds, crocodiles, ferrets and human adults. But how early in life does this a
US study suggests GLP-1 RA drugs are associated with small increase in ischemic optic neur
US study suggests GLP-1 RA drugs are associated with small increase in ischemic optic neur
A target trial emulation found that people with type 2 diabetes who started glucagon-like peptide-1 receptor agonist (GLP-1RA) therapy had a slightly higher risk of ischemic optic neuropathy (ION), a rare condition involving reduced blood flow to the optic nerve that can cause su
Raman imaging applied to cardiac tissue of Fabry disease model reveals molecular map of li
How are disease-relevant molecules distributed within tissue? What changes occur even before they become visible under the microscope? Questions such as these are crucial for early diagnosis and targeted treatment in many diseases. Researchers at the Leibniz-Institut für Analytis
Foto: Paulo Oliveira / Pexels
Combination treatment harnesses cellular recycling system to fight multiple myeloma
New research from VCU Massey Comprehensive Cancer Center provides evidence for a combination treatment strategy that uses cells' waste-removal functions to target multiple myeloma. The findings, published recently in Cell Death & Disease, show how an experimental targeted protein
KRAS-targeting drugs show promise for rare appendix cancer
Targeting mutant KRAS may offer a promising new treatment option for appendix cancer, according to research from The University of Texas MD Anderson Cancer Center published in the Journal of Hematology & Oncology.
An experimental Alzheimer's drug shows promise targeting a different brain protein, new st
An experimental drug might help slow early Alzheimer's disease in a markedly different way than today's treatments—by lowering levels of a brain protein called tau, researchers reported Tuesday.